Probability tables for exclusion of mosaicism in prenatal diagnosis

• Type: Article in International Scientific Journal
• Date: 1997

Authors

SikkemaRaddatz, B (Author) Other; CASTEDO, S (Author) FMUP; TeMeerman, GJ (Author) Other

Journal

Title: Prenatal Diagnosis

Vol. 17

Pages: 115-118

ISSN: 0197-3851

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 4 Citations

Scopus - 7 Citations

Other information

Authenticus ID: P-001-C2N

DOI: 10.1002/(

Abstract (EN): The decision concerning the number of metaphases that need to be analysed to detect mosaicism of a certain degree depends mainly, for the same confidence levels, on the culture method used (in situ or flask methods). Several probability tables, designed for either the in situ or the flask method, have been reported and can be used to assist laboratories in making the decisions referred to above. However, there are instances where part of the analysis is done using the in situ and flask methods. In such situations, the previously published tables are of limited use. We have generated a new table that can be used in such situations, as well as in cases where only the flask method is used. (C) 1997 by John Wiley & Sons, Ltd.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4