Protection of deoxyribose and DNA from degradation by using aqueous extracts of several wild plants

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Giao, MS (Author) Other; Gonzalez Sanjose, ML (Author) Other; Muniz, P (Author) Other; Rivero Perez, MD (Author) Other; Kosinska, M (Author) Other; Pintado, ME (Author) Other; F. Xavier Malcata (Author) Other

Journal

Title: Journal of the Science of Food and Agriculture

Vol. 88

Pages: 633-640

ISSN: 0022-5142

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 16 Citations

Scopus - 21 Citations

Other information

Authenticus ID: P-004-194

DOI: 10.1002/jsfa.3128

Abstract (EN): BACKGROUND: Aqueous extracts of 48 herbal plants were obtained via alternative extraction protocols, and were assayed for their capacity to protect deoxyribose and DNA itself from degradation (or, conversely, for their capacity to promote DNA degradation), using electrophoresis as analytical tool. RESULTS: For a given (constant) volume of extract, deoxyribose protection ranged from 14.13 +/- 1.35% (mean +/- SD) inhibition by dwarf mallow powder infusion, up to 106.51 +/- 15.93% inhibition by avocado powder infusion. DNA protection was tested at two extract concentrations, and was slightly greater at the higher concentration. Pro-oxidant effects were essentially absent. CONCLUSION: The anti-oxidative roles of plants upon deoxyribose and DNA displayed by our experimental results were rather promising with regards to practical applications of those plants, viz. as ingredients in the formulation of nutraceutical beverages and/or foods. (c) 2007 Society of Chemical Industry.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8