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Systemic lupus erythematosus (SLE) presenting with nephrotic syndrome and membranous glomerulopathy in a 10-year-old girl

Title
Systemic lupus erythematosus (SLE) presenting with nephrotic syndrome and membranous glomerulopathy in a 10-year-old girl
Type
Article in International Scientific Journal
Year
2005
Authors
Machado, V
(Author)
Other
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Pontes, T
(Author)
Other
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Brito, I
(Author)
FMUP
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Afonso, C
(Author)
Other
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Journal
Title: Acta PaediatricaImported from Authenticus Search for Journal Publications
Vol. 94
Pages: 1507-1509
ISSN: 0803-5253
Publisher: Wiley-Blackwell
Other information
Authenticus ID: P-000-0Z4
Abstract (EN): The authors report the case of a 10-y-old girl with clinical diagnosis of systemic lupus erythematosus (SLE), made at the age of 6 y, based upon arthritis, serositis, haematological disorder and positive antinuclear antibody. The first manifestation of disease-Raynaud's phenomenon-appeared at the age of 4 y. Seven months after the diagnosis, she developed nephrotic proteinuria with haematuria. Percutaneous renal biopsy showed membranous glomerulonephritis, the least common form of lupus nephritis. Conclusion: Intravenous cyclophosphamide therapy associated with oral prednisolone proved effective in inducing complete remission of nephrotic syndrome.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 4
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