A new approach to estimating weight change and its reference intervals during the first 96 hours of life

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Fonseca, MJ (Author) Other; Severo M (Author) FMUP; Santos, AC (Author) Other

Journal

Title: Acta Paediatrica

Vol. 104 No. S466

Pages: 1028-1034

ISSN: 0803-5253

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 3 Citations

Other information

Authenticus ID: P-00G-NWT

DOI: 10.1111/apa.12894

Abstract (EN): Aim: We aimed to apply a novel model to estimate weight change and its reference intervals during the first 96 h of life and the time of weight nadir. Methods: This study involved 1288 full-term singletons, from the Generation XXI birth cohort. Recruitment occurred between 2005 and 2006 in all five public units providing obstetrical and neonatal care in Porto, Portugal. Birthweight was abstracted from clinical records, and the subsequent newborn anthropometrics were obtained by trained examiners. Longitudinal models to estimate postnatal weight were tested and the weight ratio was calculated as the weight during 96 h of life divided by birthweight. Results: The chosen model was (weight(t)similar to 3241.442 + (-9.378) 9 t + 0.119 9 t(2) + 0.000 9 t(3) + b(Oi) + b(1i) 9 t, where t represented the newborn infant's age in hours and b(i) represented the random coefficients. The curve inflection point (nadir) was achieved at 52.3 h of life, corresponding to a loss of 218 g and a weight ratio of 0.933. We estimated that at six, 12, 24 and 36 h of life the mean weight ratio and 10th-90th percentiles were 0.978 (0.968-0.988), 0.968 (0.953-0.983), 0.951 (0.928-0.974) and 0.939 (0.909-0.969), respectively. Conclusion: This model allows a more accurate estimate of newborn weight change and its reference intervals, and estimated the nadir at 52.3 h of life, corresponding to a weight ratio of 0.933.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7