Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

• Type: Another Publication in an International Scientific Journal
• Date: 2017

Authors

Gomes, A (Author) Other; Catia Teixeira (Author) FCUP; Ferraz, R (Author) Other; Prudencio, C (Author) Other; Paula Gomes (Author) FCUP

Journal

Title: Molecules

Vol. 22 No. 2

Final page: 1743

ISSN: 1420-3049

Publisher: MDPI

Indexing

ISI Web of Knowledge - 91 Citations

Scopus - 91 Citations

Other information

Authenticus ID: P-00N-6SW

DOI: 10.3390/molecules22101743

Abstract (EN): As the incidence of diabetes continues to increase in the western world, the prevalence of chronic wounds related to this condition continues to be a major focus of wound care research. Additionally, over 50% of chronic wounds exhibit signs and symptoms that are consistent with localized bacterial biofilms underlying severe infections that contribute to tissue destruction, delayed wound-healing and other serious complications. Most current biomedical approaches for advanced wound care aim at providing antimicrobial protection to the open wound together with a matrix scaffold (often collagen-based) to boost reestablishment of the skin tissue. Therefore, the present review is focused on the efforts that have been made over the past years to find peptides possessing wound-healing properties, towards the development of new and effective wound care treatments for diabetic foot ulcers and other skin and soft tissue infections.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 18