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Advances on the molecular characterization, clinical relevance, and detection methods of Gadiform parvalbumin allergens

Title
Advances on the molecular characterization, clinical relevance, and detection methods of Gadiform parvalbumin allergens
Type
Another Publication in an International Scientific Journal
Year
2017
Authors
Fernandes, TJR
(Author)
Other
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Joana Costa
(Author)
FFUP
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Carrapatoso, I
(Author)
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Beatriz B P P Oliveira
(Author)
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Mafra, I
(Author)
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Journal
Vol. 57
Pages: 3281-3296
ISSN: 1040-8398
Publisher: Taylor & Francis
Other information
Authenticus ID: P-00M-TWP
Abstract (EN): Gadiform order includes several fish families, from which Gadidae and Merlucciidae are part of, comprising the most commercially important and highly appreciated fish species, such as cod, pollock, haddock, and hake. Parvalbumins, classified as calcium-binding proteins, are considered the main components involved in the majority of fish allergies. Nine and thirteen parvalbumins were identified in different fish species from Gadidae and Merlucciidae families, respectively. This review intends to describe their molecular characterization and the clinical relevance, as well as the prevalence of fish allergy. In addition, the main protein- and DNA-based methods to detect fish allergens are fully reviewed owing to their importance in the safeguard of sensitized/allergic individuals.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 16
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