Semen parameters and their influence on pregnancy after assisted reproduction: Report of the Hospital Centre of Porto

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Bessa, MJ (Author) Other; Rego, MC (Author) Other; rocha, e (Author) ICBAS; Pessanha, J (Author) Other; Leal, C (Author) Other; Guimaraes, JM (Author) Other; Oliveira, JC (Author) Other; sousa, m (Author) ICBAS

Journal

Title: Revista Internacional de Andrologia

Vol. 13

Pages: 27-36

ISSN: 1698-031X

Publisher: Asociacion Espanola de Andrologia

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00A-8GE

DOI: 10.1016/j.androl.2014.05.001

Abstract (EN): Introduction: Several studies analyzed the possible relationships between semen parameters and assisted reproductive technologies (ART) treatments. However, none could establish a threshold to guide in the decision of which treatment technique will be better facing spermiogram values. Objectives: A database with spermiogram and clinical parameters was built in order to search for relevant interactions between semen parameters and different ART treatment techniques. Materials and methods: A general statistical analysis evaluated semen parameters, followed by correlations to study their influence on the pregnancy rate for each type of treatment technique. Results: A predominance of teratozoospermia and asthenozoospermia was observed, with strong positive correlations between age and total motility, as well as obvious correlations between concentration and motility. Of the studied population, 41.8% went for ART consultations and presented a mean time of infertility of 2.9 years, a mean male age of 33.4 years and a mean female age of 31.9 years. Of these, 17.1% achieved a spontaneous pregnancy. Of the treatment cycles, 13.1% were by intra-uterine insemination (10.2% of clinical pregnancy rate, CP, with six newborn, NB), 24.9% by in vitro-fertilization (21.7 CP, 18 NB) and 44.9% by intracytoplasmic sperm injection (25.3% CP, 40 NB). From the analysis between semen parameters and the pregnancy rates, per type of ART technique, a significant positive correlation between techniques was found, revealing thresholds associated with the probability of a successful clinical pregnancy. Conclusions: The present results suggest that spermiogram reference limits can be developed for each treatment technique that are associated with a higher probability of achieving a clinical pregnancy.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10