Spirito-Maron Echocardiographic Score: A Marker for Morphological and Physiological Assessment of Patients with Hypertrophic Cardiomyopathy

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Rangel, I (Author) Other; Goncalves, A (Author) Other; de Sousa, C (Author) FMUP; Correia, AS (Author) Other; Pinho, T (Author) Other; Madureira, AJ (Author) Other; Martins, E (Author) FMUP; Silva Cardoso, J (Author) FMUP; Filipe Macedo (Author) FMUP; Maciel MJ (Author) FMUP

Journal

Title: Echocardiography

Vol. 31

Pages: 708-715

ISSN: 0742-2822

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 1 Citation

Scientific classification

FOS: Medical and Health sciences > Health sciences

Other information

Authenticus ID: P-009-MVV

DOI: 10.1111/echo.12471

Abstract (EN): The heterogeneous distribution of hypertrophy in hypertrophic cardiomyopathy (HCM) limits the echocardiographic conventional measurements accuracy in the evaluation of left ventricular hypertrophy (LVH). The aim of this study was to assess the correlation of the echocardiographic Spirito-Maron score (SMS) with left ventricle (LV) mass quantification by cardiac magnetic resonance (CMR) and with LV diastolic function. Methods and Results: Left ventricle diastolic function parameters, SMS, LV mass (American Society of Echocardiography formula), and maximal wall thickness (MWT) were evaluated by two-dimensional (2D) transthoracic echocardiography. The SMS was obtained by adding the MWT of 4 LV segments, at the mitral valve or papillary muscles short-axis views. Echocardiographic parameters of LVH, including SMS, were correlated with LV mass obtained by CMR and with E/e' ratio. We included 45 patients (60% male, mean age 48 +/- 18 years), who underwent 2D echocardiography. Twenty-two of them performed a CMR study. A positive correlation was found between SMS and CMR LV mass (r = 0.80; P < 0.001), whereas MWT (r = 0.62; P = 0.002) and the 2D LV mass (r = 0.60; P = 0.011) presented a lower correlation with CMR LV mass. The SMS was significantly correlated with E/e' ratio (r = 0.60; P = 0.007), whereas a nonsignificant correlation was found with MWT (r = 0.41; P = 0.081) and 2D LV mass (r = 0.22; P = 0.400). Conclusion: Spirito-Maron score presents a highly positive correlation with CMR LV mass and with diastolic dysfunction severity in HCM patients. SMS is a reliable quantitative LVH measurement method and seems to provide more comprehensive morphological and physiological information than 2D echocardiographic conventional parameters used to estimate LVH.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8