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Therapeutic potential of neuregulin-1 in cardiovascular disease

Title
Therapeutic potential of neuregulin-1 in cardiovascular disease
Type
Another Publication in an International Scientific Journal
Year
2013
Authors
Pedro Mendes Ferreira
(Author)
Other
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Gilles W De Keulenaer
(Author)
Other
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Adelino F Leite Moreira
(Author)
FMUP
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Carmen Bras Silva
(Author)
FMUP
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Journal
Title: Drug Discovery TodayImported from Authenticus Search for Journal Publications
Vol. 18 No. 17-18
Pages: 836-842
ISSN: 1359-6446
Publisher: Elsevier
Indexing
Publicação em ISI Web of Science ISI Web of Science
Pubmed / Medline
Scientific classification
FOS: Medical and Health sciences > Basic medicine
CORDIS: Health sciences
Other information
Authenticus ID: P-006-7HV
Abstract (EN): Neuregulin-1 (NRG-1)/ErbB signaling has an indispensable role in cardiac development and in the maintenance of the structural and functional integrity of the human adult heart in health and disease. Several animal studies have now demonstrated the therapeutic effects of NRG-1 during acute cardiac injury and during chronic heart failure, with improvements in cardiac performance and animal survival. Phase I and II clinical trials for chronic heart failure in humans are now in progress.
Language: English
Type (Professor's evaluation): Scientific
Notes: <a href="http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS&DestLinkType=FullRecord&KeyUT=:000324719500005">Indexado na ISI Web of Science</a>
No. of pages: 7
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