Metabolism, Biochemestry and Nutrition

Code:

AFES04

Acronym:

AFES04

Keywords
Classification	Keyword
OFICIAL	Sports Sciences

Instance: 2023/2024 - 1S

Active?	Yes
Course/CS Responsible:	2nd Cycle in Physical Activity, Exercise and Health

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
2CAFES	67	Official Plan	1	-	3	25	81

Teaching language

Suitable for English-speaking students

Objectives

1.  molecular pathways of metabolic integration associated with the production and expenditure of energy


2. metabolic adaptation in the scope of health and disease


3. metabolic adaptation induced by exercise and training in different organs and systems


4. metabolic adaptation induced by exercise in metabolic dysfunction underlying several pathologies


5.  biochemical and molecular mechanisms, as well as with essential determinants that result from the use and implication of nutritional recommendations appropriate to different contexts.

Learning outcomes and competences

Students must:
- understand different variants of metabolic integration in the context of health, illness and physical exercise;
-understand molecular mechanisms of cell modeling and signaling associated with changes in genotype and phenotype indifferent contexts;
- know the nutritional recommendations and understand the role of adequate nutrition / nutrition in promoting health and preventing disease.

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

Cellular Biology, Human Physiology and Biochemistry

Program

1. Biochemistry concepts




1. Cell Structure


2. Structure and function of carbohydrates, lipids and proteins


3. Relevance of proteins, carbohydrates and lipids for Sports and exercise




2. Metabolic integration and regulation in health and disease




1. Principles of metabolic regulation




1. Anabolism and catabolism metabolism and energy


2. The endocrine control and integration of metabolism


3. Overview of major metabolic pathways and strategy for energy conservation




2. Roles of different organ in the integration of metabolic 


3. The impact of metabolic dysfuntion in several emergents pathologies focusing on obesity, diabtes and cancer




3. Metabolic Regulation during exercise 




1. Overview of energy production and metabolic regulation in high-intensity exercise




1. Effects of exercise duration


2. Effects of training


3. Mechanisms of fatigue




2. Overview of energy production and metabolic regulation in endurance exercise




1. Effects of exercise duration and intensity


2. Effects of training


3. Mechanisms of fatigue




3. Overview of energy production and metabolic regulation in high-intensity intermittent exercise




1. Muscle adaptations to interval training


2. Mechanisms of fatigue






4. 
   
   Specialized topics on metabolic adaptation in exercise and health
   
   




1. Metabolic adapation of skeletal muscle in response to acute and prolonged exercise and  in disease such as sarcopenia, metabolic syndrome and caquexia.


2. Metabolic adapations in several tissue such as skeletal muscle, liver, adipose tisse, heart and brain duting exercise.




5. 
   
   Dietary guidelines
   
   


6. 
   
   Factors that influence nutritional quality and food choices
   
   


7. 
   
   Health promotion and disease prevention through diet
   
   

Mandatory literature

Don Maclaren & James Morton; Biochemistry for Sport and Exercise Metabolism, Wiley-Blackwell, 2012. ISBN: 978-0-470-09184-2
Ron Maughan & Michael Gleeson. ; The Biochemical Basis Of Sports Performance, Oxford University Press, 2010
Glenn McConel; Exercise Metabolism (Physiology in Health and Disease), Springer, 2022
Eric Newsholme & Tony Leech; Functional Biochemistry in Health and Disease, Wiley-Blackwell, 2009
John Baynes & Marek Dominiczak; Medical Biochemistry, Elsevier, 2019
EFSA (European Food Safety Authority); Dietary Reference Values for nutrients Summary Report, 2017
Christine Karpinski, Christine A. Rosenbloom; Sports Nutrition: A Handbook for Professionals, 6th Edition, Academy of Nutrition and Dietetics, 2017. ISBN: 978-0880919753
Dr. Paul Insel, Don Ross, Kimberley McMahon, Melissa Bernstein; Nutrition 6th Edition, Jones & Bartlett Learning, 2017. ISBN: 978-1284100051
Bruke L. & Deakin V; Clinical Sports Nutrition 5th Edition, MCGRAW-HILL EDUCATION, 2015. ISBN: 9781743073681
D Travis Thomas, Kelly Anne Erdman, Louise M Burke; American College of Sports Medicine Joint Position Statement. Nutrition and Athletic Performance, Med Sci Sports Exerc, 2016. ISBN: : 10.1249/MSS.0000000000000852

Complementary Bibliography

Alexandre Quintas; Bioquímica. ISBN: 978-972-757-431-5
David L. Nelson; Lehninger. ISBN: 978-1-4641-2611-6

Teaching methods and learning activities

The classes have an expository character, always looking for the active participation of students through questions and problems raised by the teacher related to the topics.

keywords

Natural sciences > Biological sciences > Biology
Health sciences > Medical sciences > Medicine > Physiology
Physical sciences > Chemistry > Biochemistry > Metabolism

Evaluation Type

Evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	100,00
Total:	100,00

Amount of time allocated to each course unit

designation	Time (hours)
Estudo autónomo	30,00
Frequência das aulas	25,00
Total:	55,00

Eligibility for exams

Students will be assessed by a final exam. To perform this final examination, students must attend 75 % of lessons. The approval to the UC is achieved with the minimum of 9,5 values.

Calculation formula of final grade

The evaluation of the students is according with the legal roles established by University of Porto as well as with those defined by the Pedagogic Council from the Faculty of Sport. Regarding the exam of the CU, two evaluation moments will be considered as 1st and 2nd seasons. It is important to note that the score obtained in test cannot be lower than 9.5 values. For those students who do not achieve positive score during the 1st season, they can be under evaluation during the 2nd season, in which they also need to obtain a minimum score of 9.5 values. The final score of the test will be adjusted for unit values (without decimal places).
The final result of the CU exam will correspond to 100% of final classification.
Taking into account the uncertainties associated to the pandemic condition of COVID-19, the evaluation of the students will be performed in regular conditions in the Faculty or, in alternative, online in the e-learning platform Moodle.