Uniaxial mechanical behavior of the human female bladder

• Tipo: Artigo em Revista Científica Internacional
• Data: 2011

Autores

Pedro A L S Martins (Autor) Outra; Agnaldo Lopes Silva Filho (Autor) Outra; Andrea Moura R M Rodrigues Maciel Fonseca (Autor) Outra; Agostinho Santos (Autor) Outra; Liliana Santos (Autor) Outra; Teresa Mascarenhas (Autor) FMUP; Renato M N Natal Jorge (Autor) FEUP; Antonio J M Ferreira (Autor) FEUP

Revista

Título: International Urogynecology Journal

Vol. 22 Nº Suppl. 1

Páginas: 991-995

ISSN: 0937-3462

Indexação

ISI Web of Knowledge - 44 Citações

ISI Web of Science

Scopus - 43 Citações

Pubmed / Medline

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

CORDIS: Ciências Tecnológicas > Engenharia > Engenharia biomédica

Outras Informações

ID Authenticus: P-002-P1F

DOI: 10.1007/s00192-011-1409-0

Abstract (EN): Introduction and hypothesis The objective of the present study was to investigate the tensile biomechanical properties of the human female bladder. Methods Tissue samples were obtained from 13 cadavers without pelvic floor dysfunctions. We performed uniaxial tensile tests to measure the stiffness and maximum stress of the bladder tissue. Correlations were calculated using the Pearson correlation coefficient. Results The bladder tissue stiffness ranged from 1 to 4.1 MPa (mean stiffness, 1.9 +/- 0.2 MPa) and the maximum stress ranged from 0.5 to 2.6 MPa (mean maximum stress, 0.9 +/- 0.1 MPa). There was a strong positive correlation between stiffness and maximum stress in the bladder tissue (rho=0.829, p<0.001). Tissue from women younger than 50 years presented higher bladder stiffness than did tissue from older subjects (2.1 +/- 0.2 versus 1.3 +/- 0.1 MPa, p=0.02). Maximum bladder stress, however, was not associated with age (1.0 +/- 0.2 versus 0.7 +/- 0.1 MPa, p=0.349). In addition, body mass index and menopausal status were not associated with these biomechanical properties. Conclusions Age may influence the uniaxial mechanical behavior of the human female bladder.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5