FEM simulation and experimental determination of the temperature profile of nanoparticles excited by laser radiation

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2014

Autores

Nuno F G Rodrigues (Autor) Outra; Carla C Rosa (Autor) FCUP; Joao M P Coelho (Autor) Outra

Ata de Conferência Internacional

Título: SECOND INTERNATIONAL CONFERENCE ON APPLICATIONS OF OPTICS AND PHOTONICS

2nd International Conference on Applications of Optics and Photonics

Aveiro, PORTUGAL, MAY 26-30, 2014

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia electrotécnica, electrónica e informática

Outras Informações

ID Authenticus: P-009-X5B

DOI: 10.1117/12.2063838

Abstract (EN): Cancer cells can be easily killed when they reach a temperature above 40 degrees. This is known as hyperthermia and the incorporation of nanoparticles (NPs) is helpful to locally rise the temperature. The local heating of NPs could also be used to deliver drugs encapsulated in a specific location inside a body. To achieve the local heating it is necessary to know the temperature profile of the NPs when excited by laser radiation. The COMSOL software was used to simulate the temperature profile of the NPs in an aqueous solution (the cells are mainly composed of water). An analysis is made regarding the temperature rise for different irradiation parameters, NPs concentration and the corresponding potential of locally affecting cancerous cells without significantly affecting adjacent healthy cells.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5