SKELETAL-MUSCLE DAMAGE DURING TOURNIQUET-INDUCED ISCHEMIA - THE INITIAL STEP TOWARDS ATROPHY AFTER ORTHOPEDIC-SURGERY

• Tipo: Artigo em Revista Científica Internacional
• Data: 1993

Autores

appell, hj (Autor) Outra; gloser, s (Autor) Outra; duarte, jar (Autor) FADEUP; zellner, a (Autor) Outra; soares, jmc (Autor) Outra

Revista

Título: European Journal of Applied Physiology and Occupational Physiology

Vol. 67

Páginas: 342-347

ISSN: 0301-5548

Editora: Springer

Indexação

ISI Web of Knowledge - 47 Citações

Scopus - 52 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina básica

Outras Informações

ID Authenticus: P-001-MK9

DOI: 10.1007/bf00357633

Abstract (EN): Muscle biopsies from the vastus lateralis muscle of patients who had undergone anterior cruciate ligament surgery under conditions of tourniquet-induced ischaemia were examined under the electron microscope at different periods of time up to 90 min of ischaemia. The severity of the alterations in ultrastructure appeared to depend on the period of ischaemia. The pathological changes consisted of accumulation of lysosomes, persistent intrafibre oedema, and some extracellular oedema. Signs of fibre necrosis were found after 90 min of ischaemia. Capillary ultrastructure was only altered with regard to some swelling of the endothelium and marked thickening of the basement membrane. It was concluded that skeletal muscle could be severely affected even during relatively short periods of ischaemia, which might facilitate the development of muscle atrophy during immobilization after orthopaedic surgery.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 6