Fully automated spectrophotometric method for the determination of buspirone in pharmaceutical preparations

• Tipo: Artigo em Revista Científica Internacional
• Data: 2006

Autores

Marta F T Ribeiro (Autor) Outra; Joao L M Santos (Autor) FFUP; Jose L F C Lima (Autor) FFUP; Ana C B Dias (Autor) Outra; Elias A G Zagatto (Autor) Outra

Revista

Título: Analytical Letters

Vol. 39 Nº 11

Páginas: 2243-2253

ISSN: 0003-2719

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 5 Citações

ISI Web of Science

Scopus - 7 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

CORDIS: Ciências da Saúde

Outras Informações

ID Authenticus: P-004-P3J

DOI: 10.1080/00032710600755348

Resumo (PT): A fully automated kinetic method for the spectrophotometric determination of buspirone in pharmaceutical preparations is proposed. The analytical system was implemented by using multiple solenoid micropumps for sample and reagents insertion, which led to improved operational simplicity and low reagent consumption. A three-way solenoid valve enabled the establishment of two parallel reactors and the exploitation of the fixed time approach for differential kinetics. Linear calibration plots for buspirone concentrations of up to 60mgL21 were obtained, with a detection limit of 2.8mgL21. The sampling rate was about 55 samples per hour. <br> <br> Keywords: Multipumping flow analysis, spectrophotometry, buspirone, Folin- Ciocalteu reagent <br> <a target="_blank" href="http://www.informaworld.com/smpp/content~db=all~content=a749252619 "> Texto integral </a> <br> <br>

Abstract (EN): A fully automated kinetic method for the spectrophotometric determination of buspirone in pharmaceutical preparations is proposed. The analytical system was implemented by using multiple solenoid micropumps for sample and reagents insertion, which led to improved operational simplicity and low reagent consumption. A three-way solenoid valve enabled the establishment of two parallel reactors and the exploitation of the fixed time approach for differential kinetics. Linear calibration plots for buspirone concentrations of up to 60 mgL(-1) were obtained, with a detection limit of 2.8 mgL(-1). The sampling rate was about 55 samples per hour.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11