Bromelain-loaded nanoparticles: A comprehensive review of the state of the art

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2018

Autores

Ataide, JA (Autor) Outra; Gérios, EF (Autor) Outra; Mazzola, PG (Autor) Outra; Souto, EB (Autor) Outra

Revista

Título: Advances in Colloid and Interface Science

Vol. 254

Páginas: 48-55

ISSN: 0001-8686

Editora: Elsevier

Indexação

ISI Web of Knowledge - 27 Citações

Scopus - 10 Citações

Outras Informações

ID Authenticus: P-00N-V1Y

DOI: 10.1016/j.cis.2018.03.006

Abstract (EN): Stem bromelain is a common available cysteine protease derived from pineapple (Ananas comosus L.). Bromelain finds widespread applications in several areas, such as medicine, health, food, and cosmetics, and its strong proteolytic activity supports its future application in many additional fields. However, most proteins and/or enzymes are fragile, leading to important considerations about increase storage and operational stability to enable their practical application. In this scenario, the use of nanoparticles to deliver proteins is increasing exponentially, given that these systems are capable of enhance active's stability, solubility and permeability, and decrease toxicity. In the pharmaceutical nanotechnology field, bromelain has played different roles and thus this paper aims to review the available literature for the use of nanoparticles and bromelain. © 2017

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8