In vitro cytocompatibility of osteoblastic cells cultured on chitosan-organosiloxane hybrid membrane

• Tipo: Artigo em Revista Científica Internacional
• Data: 2004

Autores

Y. Shirosaki (Autor) Outra; K. Tsuru (Autor) Outra; S. Hayakawa (Autor) Outra; A. Osaka (Autor) Outra; Maria Ascensão Lopes (Autor) FEUP; José Domingos Santos (Autor) FEUP; Maria Helena Fernandes (Autor) FMDUP

Revista

A Revista está pendente de validação pelos Serviços Administrativos.

Título: BIOCERAMICS, VOL 16

Vol. 254-256

Páginas: 857-860

Indexação

ISI Web of Knowledge - 4 Citações

ISI Web of Science

Scopus - 3 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Biotecnologia ambiental

Outras Informações

ID Authenticus: P-000-CBQ

DOI: 10.4028/www.scientific.net/KEM.254-256.857

Abstract (EN): Chitosan-silicate hybrids were synthesized using gamma-glycidoxypropyltrimethoxysilane (GPSM) as the agent to cross-link the chitosan chains. Fourier-transform infrared (FT-IR) spectroscopy was used to analyze the structures of the hybrids. The swelling ability and the cytocompatibility of the hybrids were investigated as a function of the GPSM concentration. The swelling of the hybrids was suppressed by addition of GPSM. MG63 human osteoblastic cells were cultured on the hybrids. The adhesion and proliferation of the MG63 cells cultured on the chitosan-GPSM hybrid surface were improved comparing to that on chitosan membrane, regardless the GPSM concentration.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4