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An optimization-simulation approach to the network redesign problem of pharmaceutical wholesalers

Título
An optimization-simulation approach to the network redesign problem of pharmaceutical wholesalers
Tipo
Artigo em Revista Científica Internacional
Ano
2017-02-06
Revista
Vol. 106
Páginas: 315-328
ISSN: 0360-8352
Editora: Elsevier
Indexação
Outras Informações
ID Authenticus: P-00M-GGH
Abstract (EN): The pharmaceutical industry operates in a very competitive and regulated market The increased pressure of pharmacies to order fewer products and to receive them more frequently is overcharging the pharmaceutical's distribution network Furthermore, the tight margins and the continuous growth of generic drugs consumption are pressing wholesalers to optimize their supply chains. In order to survive, wholesalers are rethinking their strategies to increase competitiveness. This paper proposes an optimization-simulation approach to address the wholesalers network redesign problem, trading off the operational costs and customer service level. Firstly, at a strategic-tactical level, the supply chain network redesign decisions are optimized via a mixed integer programming model. Here, the number, location, function and capacity of the warehouses, the allocation of customers to the warehouses and the capacity and function of the distribution channels are defined. Secondly, at an operation level, the solution found is evaluated by means of a discrete event simulation model to assess the impact of the redesign in the wholesaler's daily activities. Computational results on a pharmaceutical wholesaler case-study are discussed and the benefits of this solution approach exposed.
Idioma: Inglês
Tipo (Avaliação Docente): Científica
Nº de páginas: 14
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