A Parameter Estimation Process for Improved Drug Infusion

• Type: Article in International Conference Proceedings Book
• Date: 2025

Authors

Hugo Alonso (Author) Other; Mendonça, T (Author) Other; Rocha, P (Author) FEUP

Conference proceedings International

Title: CONTROLO 2024

Pages: 140-150

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-018-TRK

DOI: 10.1007/978-3-031-81724-3_14

Abstract (EN): In this paper, we consider a reduced parameter (RP) model for the effect of the drug atracurium on the neuromuscular blockade (NMB) level of patients undergoing general anesthesia. We propose a generalization of a previously introduced parameter estimation process to obtain the patient dependent parameters of the RP model. Furthermore, we consider a reference tracking problem, where the objective is to force the NMB level of the patients to follow a constant reference, and suggest an open-loop control law based on the estimated RP model. It turns out that the application of the identification process requires choosing two values. In this context, we present an experimental study whose goal is to clarify how these choices impact on the results of the reference tracking problem. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10