Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

• Type: Another Publication in an International Scientific Journal
• Date: 2011

Authors

Badve, S (Author) Other; Dabbs, DJ (Author) Other; Schnitt, SJ (Author) Other; Baehner, FL (Author) Other; Decker, T (Author) Other; Eusebi, V (Author) Other; Fox, SB (Author) Other; Ichihara, S (Author) Other; Jacquemier, J (Author) Other; Lakhani, SR (Author) Other; Palacios, J (Author) Other; Rakha, EA (Author) Other; Richardson, AL (Author) Other; Fernando Schmitt (Author) FMUP; Tan, PH (Author) Other; Tse, GM (Author) Other; Weigelt, B (Author) Other; Ellis, IO (Author) Other; Reis Filho, JS (Author) Other

Journal

Title: Modern Pathology

Vol. 24 No. 157-167

Pages: 157-167

ISSN: 0893-3952

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 461 Citations

Scopus - 495 Citations

Other information

Authenticus ID: P-002-VP9

DOI: 10.1038/modpathol.2010.200

Abstract (EN): Breast cancer is a heterogeneous disease encompassing a variety of entities with distinct morphological features and clinical behaviors. Although morphology is often associated with the pattern of molecular aberrations in breast cancers, it is also clear that tumors of the same histological type show remarkably different clinical behavior. This is particularly true for 'basal-like cancer', which is an entity defined using gene expression analysis. The purpose of this article was to review the current state of knowledge of basal-like breast cancers, to discuss the relationship between basal-like and triple-negative breast cancers, and to clarify practical implications of these diagnoses for pathologists and oncologists. Modern Pathology (2011) 24, 157-167; doi:10.1038/modpathol.2010.200; published online 12 November 2010

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11