Você está em: Start > Laboratory of Organic and Pharmaceutical Chemistry-Artificial Molecular Recognition
In this field of research, we are developing the following studies:
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors Gupta S, Rodrigues LM, Oliveira-Campos AM, Esteves AP, Nascimento MSJ, Nazareth N, Cidade H, Neves MP, Pinto M, Fernandes E, Cerqueira NM, Brás N European Journal of Medicinal Chemistry, 43, 771-780. 2008 Multimilligram enantioresolution of low-solubility xanthonolignoids on polysaccharide chiral stationary phases using a solid-phase injection system E Sousa, ME Tiritan, KRA Belaz, M Pedro, MSJ Nascimento, QB Cass, MMM Pinto J. Chromatography A, 1120, 75-81. 2006 Psoralen analogues: Synthesis, Inhibitory Activity of Growth of Human Tumor Cell Lines and Computational Studies Oliveira AMAG, Raposo MMM, Oliveira-Campos AMF, Machado AEH, Puapairoj P, Pedro M, Nascimento MSJ, Portela C, Afonso C, Pinto M European Journal of Medicinal Chemistry, 41, 367-372. 2006 The binding of xanthone derivatives to transthyretin Maia F, Almeida MR, Gales L, Kijjoa A, Pinto MMM, Saraiva MJ, Damas AM Biochemical Pharmacology, 70, 1861-1869. 2005
Fases Estacionárias Quirais baseadas em Derivados Xantónicos Pinto M, Tiritan ME, Fernandes C, Cass Q Portuguese Patente nº 104679 (pending)
Development of siRNA-loaded nanoparticles to circumvent chemoresistance in cancer stem cells Project I&D em todos os Domínios Científicos - 2008 PTDC/EBB-BIO/099672/2008, in collaboration with IPATIMUP, 3 years, 2009 Chiral xanthones derivatives: synthesis, enantiomeric resolution, anti-inflammatory and antioxidant evaluations Project 10-GCQF-CICS-09, GCQF - CICS/CESPU, in collaboration with CESPU, 24 months, 2009 Chiral Xanthones: Synthesis, Structure Elucidation, Enantiomeric Purity and Antioxidant and Anti-inflammatory Activities Multidisciplinary Project, University of Porto, in collaboration with undergraduate students, 15 mounths, 2009 Searching for small-molecule modulators of caspase family members using yeast cell-based approaches Multidisciplinary Project, University of Porto, in collaboration with undergraduate students, 15 mounths, 2009 Virtual screening and in vitro evaluation of antitumour xanthones for anti-EBV activity in a Burkitt lymphoma cell line Multidisciplinary Project, University of Porto, in collaboration with undergraduate students, 15 mounths, 2009 Chiral Xanthones Derivatives: Synthesis, Structural Elucidation and Biological Activities Multidisciplinary Project, University of Porto, in collaboration with undergraduate students and Institute of Biomedical Sciences, (2007-2008) Chiral xanthonic derivatives: enantiomeric resolution, biological activities and application as new chiral selectors for HPLC Bilateral Cooperation between Research Center of Organic Chemistry, Phytochemistry and Pharmacology of the University of Porto Faculty of Pharmacy of the University of Porto and Department of Chemistry of University of São Carlos, Brazil, GRICES/CAPES, (2002-2006) |
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Last update: 2015-07-24 I Page created on: 2024-05-05 at 07:17:38 | Acceptable Use Policy | Data Protection Policy | Complaint Portal
Last update: 2015-07-24 I Page created on: 2024-05-05 at 07:17:38 | Acceptable Use Policy | Data Protection Policy | Complaint Portal