Predictors of cognitive stability or decline during aging: A longitudinal study in primary care

• Tipo: Artigo em Revista Científica Internacional
• Data: 2020

Autores

Martins, IP (Autor) Outra; Maruta, C (Autor) Outra; Morgado, J (Autor) Outra; Loureiro, C (Autor) Outra; Tavares, J (Autor) Outra; Freitas, V (Autor) Outra; Lunet N (Autor) FMUP; Viana, P (Autor) Outra; Marques, P (Autor) Outra

Revista

Título: Applied Neuropsychology: Adult

Vol. 27 Nº 6

Páginas: 22-34

ISSN: 2327-9109

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 4 Citações

Scopus - 2 Citações

Outras Informações

ID Authenticus: P-00P-M4T

DOI: 10.1080/23279095.2018.1476866

Abstract (EN): We aimed to identify the early predictors of cognitive decline, and primary care physicians' (PCP) ability to diagnose cognitively impaired subjects, in a cohort of individuals recruited in primary care centers. Independent adults, aged >= 50 years at inception, with an overall low level of education, undertook a prospective clinical and cognitive evaluation targeting memory, attention and executive functions. At follow-up subjects were classified as cognitively normal (CN) or impaired (CI). Of 275 subjects (70.4 +/- 8.3 years old, 176 females, 7.5 +/- 4.4 education, 162 with MRI), 31 (11.2%) presented CI 4.9 years later, the majority (64.5%) presenting subjective cognitive complaints. PCP could correctly identify 40% of CI individuals, particularly if they presented current cognitive complaints. Male sex (OR = 3.117; CI95%: 1.007-9.645), age (OR = 1.063; CI95%: 1.004-1.126) and baseline scores on TMT-B (OR = 0.225; CI95%: 0.073-0.688) and Vocabulary (OR = 0.940; 95% CI: 0.894-0.986) predicted CI. This study shows that measures indicating poor cognitive reserve and low executive performance (as shown by low vocabulary and executive test scores, respectively) can be early indicators of the risk of decline, stressing the role of cognitive assessment as part of prevention/early intervention programs. The results also underline the need to help PCP to improve the detection of subjects with cognitive decline.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13