An Active Surface Preservation Strategy for the Rational Development of Carbon Dots as pH-Responsive Fluorescent Nanosensors

• Tipo: Artigo em Revista Científica Internacional
• Data: 2021

Autores

Afonso, ACP (Autor) Outra; Correia, AS (Autor) Outra; Duarte, D (Autor) Outra; Brandao, ATSC (Autor) FCUP; de Yuso, MDM (Autor) Outra; Jimenez Jimenez, J (Autor) Outra; Nuno Vale (Autor) FMUP; Carlos M Pereira (Autor) FCUP; Algarra, M (Autor) Outra; da Silva, LP (Autor) FCUP

Revista

A Revista está pendente de validação pelos Serviços Administrativos.

Título: CHEMOSENSORS

Vol. 18

Página Final: 191

Indexação

ISI Web of Knowledge - 11 Citações

Scopus - 10 Citações

Outras Informações

ID Authenticus: P-00V-5N1

DOI: 10.3390/chemosensors9080191

Abstract (EN): Here we report the rational development of a carbon dot (CDs)-based fluorescent pH nanosensor by employing an active surface preservation strategy. More specifically, citric acid, urea and fluorescein were subjected to a one-pot hydrothermal treatment, which preserved fluorescein-like structures on the surface of the CDs. The obtained CDs showed pH-sensitive green emission, which can be used to determine pH variations from 3.7 to 12.1 by fluorescence enhancement. Moreover, the obtained nanoparticles showed excellent selectivity toward pH, fluorescence reversibility in different pH values, photostability, while being compatible with human cell lines (even at high concentrations). Furthermore, their performance as pH sensors was comparable with reference pH determination procedures. Thus, an active surface preservation strategy was successfully employed to develop fluorescence pH nanosensors in a rational manner and without post-synthesis functionalization strategies, which show potential for future use in pH determination.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13