Resumo (PT):
Abstract (EN):
Alzheimer’s disease is a progressive and irreversible neurodegenerative disease that affects millions of people globally. Presently, AD is considered a serious health concern, a
social and economic burden. There is still no medically accepted cure for AD. Current therapeutics that are marketed
for AD treatment only attenuate the symptoms and have
several side effects. To avoid the side effects associated with
synthetic drugs, natural compounds have gained huge attention in the last 20 years, since they have been part of our
common diet and have shown neuroprotective effects. This
chapter presents a brief review on the existing medication
and ongoing research on natural compounds in clinical trials
for AD treatment. However, natural compounds alone have
low permeability through the Blood Brain Barrier (BBB) and
have low bioavailability. Therefore, a combination of natural
compounds with nanocarriers could be a potential therapeutic strategy for AD.
Idioma:
Inglês
Tipo (Avaliação Docente):
Científica
Nº de páginas:
5