A finite element model to predict the consequences of endolymphatic hydrops in the basilar membrane

• Type: Article in International Scientific Journal
• Date: 2021

Authors

Areias, B (Author) Other; Parente, MPL (Author) FEUP; Gentil, F (Author) Other; Caroca, C (Author) Other; Paco, J (Author) Other; Renato Natal Jorge (Author) FEUP

Journal

Title: International Journal for Numerical Methods in Biomedical Engineering

ISSN: 2040-7939

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00V-KMM

DOI: 10.1002/cnm.3541

Abstract (EN): Meniere's disease is an inner ear disorder, associated with episodes of vertigo, fluctuant hearing loss, tinnitus, and aural fullness. Meniere's disease is associated with endolymphatic hydrops. Clinical evidences show that this disease is often incapacitating, negatively affecting the patients' everyday life. The pathogenesis of Meniere's disease is still not fully understood and remains unclear. Previous numerical studies available in the literature related with endolymphatic hydrops, are very scarce. The present work applies the finite element method to investigate the consequences of endolymphatic hydrops in the normal hearing, associated with the Meniere's disease. The obtained results for the steady state dynamics analysis are in accordance with clinical evidences. The results show that the basilar membrane is not affected in the same intensity along its length and that the lower frequencies are more affected by the endolymphatic hydrops. From a clinical point of view, this work shows the relationship between the increasing of the endolymphatic pressure and the development of hearing loss.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 13