Oncobiology

Code:

CM4001

Acronym:

CM4001

Keywords
Classification	Keyword
OFICIAL	Medical Sciences

Instance: 2015/2016 - 1S

Active?	Yes
Responsible unit:	Molecular Pahology and Immunology
Course/CS Responsible:	Master in Biochemistry

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
M:BQ	6	Plano de Estudos do MBIOQ_2013-2014	1	-	6	56	162

Teaching language

Suitable for English-speaking students

Objectives

Recognize the main types of human cancer and its time trends; Identify the main phases of neoplastic development; recognize the molecular / genetic basis of cancer; Understand the carcinogenic process as the result of interaction between host and environment; Identify the main hereditary conditions associated with predisposition to cancer; Recognize therapeutic strategies based on the molecular characterization of cancer.

Learning outcomes and competences

Acquire basic concepts about classification and epidemiological characteristics of the main types of neoplasia; Recognize cancer as the result of cumulative genomic alterations and the interaction of the host with the environment; Understand the main mechanisms underlying the progress of cancer; Identify the most frequent situations of hereditary predisposition to cancer; Understand the rationale for cancer targeted therapy; Recognize the main research fields in Oncology and their potential impact in medical practice.

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

Basic knowledge of histology, physiology and genetics

Program

Neoplasia and lesional mechanisms: bases for classification; Epidemiology: incidence, prevalence and time trends; Methodologies for the study of cancer; Biology of the neoplastic cell: differentiation, growth, and progression; Molecular bases of cancer: cell cycle, apoptosis, oncogenes, tumor suppressor genes and caretaker genes, mechanisms of invasion, angiogenesis, and metastasis, interaction neoplasia / stroma, mechanisms of gene disregulation in cancer; Carcinogenic agents: chemical, physical, and biological; Inflammation and cancer; Hereditary predisposition for cancer; Clinical manifestations; Targeted therapy for cancer; Research in Oncology.

Mandatory literature

Kumar Vinay 070; Robbins and Cotran pathology basis of disease. ISBN: 0-7216-9274-5 (Chapter 7: Neoplasia)

Comments from the literature

Relevant publications concerning the themes dealt with in the classes will be provided

Teaching methods and learning activities

Theoretical sessions and theoretical/practical lab sessions (when possible)

Software

Moodle Universidade do Porto

keywords

Health sciences > Medical sciences > Medicine > Oncology
Health sciences > Medical sciences > Medicine > General pathology
Natural sciences > Biological sciences > Biology > Genetics

Evaluation Type

Evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	100,00
Total:	100,00

Eligibility for exams

Attendance of at least 75% of the theoretical/practical sessions

Calculation formula of final grade

Classification obtained in the final exam

Examinations or Special Assignments

Not applicable

Internship work/project

Not applicable

Special assessment (TE, DA, ...)

According to the Standards for Evaluation and Pedagogical Orientation of the University of Porto

Classification improvement

New assessment in the appeal season

Observations

The sessions take place at the Portuguese Oncology Institute - Porto