Basic Genetics

Code:

MT119

Acronym:

G_BASI

Keywords
Classification	Keyword
OFICIAL	Medicine

Instance: 2005/2006 - 1S

Active?	Yes
Responsible unit:	Population Studies
Course/CS Responsible:	Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MED	184	Plano oficial a partir de 2003	1	3		-

Objectives

To introduce and stimulate in the students:
(i) a biological thought of integrated systems of cells, tissues and organisms and not of cells, tissues and isolated organisms;
(ii) the ability to formulate mathematical models from these situations, identifying and using the appropriate concepts and mathematical techniques;
(iii) the aptitude to value the adaptation of the model to the system that is intended to describe, namely through the critical interpretation of the results.

Program

A short history of Genetics, big "divisions" /great divisions of Genetics.
The importance of Genetics in Medicine. Effects of genes in health and disease
The Human Genome Project and its applications in Medicine.
Formal genetics.

Main Bibliography

Lewis, Ricki, Human Genetics, Concepts and Applications, 5th ed, Mc Graw Hill, 2003
(especialmente capítulos 4, 5, 6, 7, 13 e 14)
- Griffiths, AJF, Miller JH, Suzuki D T, Lewontin R C, Gelbart WM, An Introduction to Genetic Analysis, W.H. Freeman and Company, NY, 2000
- Alstad D. Basic POPULUS Models of Ecology, Prentice Hall, Upper Saddle River, NJ, 2001
- Krebs, CJ. Ecology: The Experimental Analysis of Distribution and Abundance. Harper Collins College Pub., New York, 1994.
- Hartl D. A primer of Population Genetics. Sinauer Pub., 3rd ed., 2000.

Complementary Bibliography

- Andersson RM, May RM, Infectious Disease in Humans, Oxford University Press, NY, 1991
- Crow J e Kimura M. An Introduction to Population Genetics. Harper and Row, New York, 1970.
- Li CC. First Course in Population Genetics. Boxwood Press, Pacific Grove
- Vogel F e Motulsky A. Human Genetics (Problems and Approaches), 3rd ed., Springer-Verlag, Berlin, 1997.
- Cavalli-Sforza LL e Bodmer W F. The Genetics of Human Populations. W. H. Freeman and Co., San Francisco, 1971.

Teaching methods and learning activities

Lectures and seminars

Practical sessions involving exercises, mechanical simulations and computer simulations

Software

http://ecology.umn.edu/populus (Programa POPULUS) http://www3.ncbi.nlm.nih.gov/omim (Online Mendelian Inheritance in Man) http://www3.ncbi.nlm.nih.gov/entrez (PubMed) http://www.genome.gov/glossary.cfm www.whfreeman.com/pierce/ (Genetics - Pierce) www.whfreeman.com/iga/ (Introduction to Genetic Analysis - Griffiths )

Evaluation Type

Distributed evaluation with final exam

Eligibility for exams

According to the general Law (2/3 practical classes)

Calculation formula of final grade

Arithmetical average of two tests or score obtained in final examination