Spray Drying: An Overview

• Tipo: Capítulo ou Parte de Livro
• Data: 2018

Autores

Daniel Santos (Autor) Outra; Ana Colette Maurício (Autor) Outra; Vitor Sencadas (Autor) Outra; José Domingos Santos (Autor) FEUP; Maria H. Fernandes (Autor) FMDUP; Pedro S. Gomes (Autor) FMDUP

Livro

Título: Biomaterials - Physics and Chemistry - New Edition

Páginas: 9-35

ISBN: 9781789230642

ISBN Eletrónico: 9781789230659

Outras Informações

ID Authenticus: P-00R-8KV

DOI: 10.5772/intechopen.72247

Abstract (EN): Spray drying is a well-known method of particle production which comprises the transformation of a luid material into dried particles, taking advantage of a gaseous hot drying medium, with clear advantages for the fabrication of medical devices. In fact, it is quite common the production of microspheres and microcapsules designed for drug delivery systems. This review describes the diferent stages of the mechanism of the spray-drying process: atomization, droplet-to-particle conversion and particle collection. In particular, this work addresses the diversity of available atomizers, the drying kinetics and the importance of the coniguration of the drying chamber, and the eiciency of the collection devices. The inal properties of the dried products are inluenced by a variety of factors, namely the spray dryer design, the feed characteristics and the processing parameters. The impact of those variables in optimizing both the spray-drying process and the synthesis of dried particles with desirable characteristics is discussed. The scalability of this manufacturing process in obtaining dried particles in submicron-to-micron scale favors a variety of applications within the food, chemical, polymeric, pharmaceutical, biotechnology and medical industries

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 27