EFFECT OF COOKING ON DIAZEPAM AND ITS METABOLITES IN LIVER OF BULLS

• Tipo: Artigo em Revista Científica Internacional
• Data: 1993

Autores

BASTOS, MD (Autor) FFUP; SOARES, ME (Autor) Outra

Revista

Título: Journal of Agricultural and Food Chemistry

Vol. 41

Páginas: 965-967

ISSN: 0021-8561

Editora: American Chemical Society

Indexação

ISI Web of Knowledge - 2 Citações

Scopus - 2 Citações

Classificação Científica

FOS: Ciências agrárias > Outras ciências agrárias

Outras Informações

ID Authenticus: P-001-N1N

DOI: 10.1021/jf00030a025

Abstract (EN): The stability of residues of diazepam and its metabolites (oxazepam, temazepam, and demethyldiazepam) in the liver of treated bulls when subjected to a heating procedure (100-degrees-C in water for 1 h) was studied. Compounds were quantified by reversed-phase high-performance liquid chromatography using ultraviolet detection. The most unstable of the compounds studied was, under those conditions, oxazepam, which was degraded to approximately 50% of the original quantities. The other compounds were more stable and, after treatment, were present in 70-89% of the initial quantity.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3