Introduction to Human Genetics

Code:

P110

Acronym:

IGH

Keywords
Classification	Keyword
OFICIAL	Behavior Biology

Instance: 2019/2020 - 2S

Active?	Yes
Responsible unit:	Psychology
Course/CS Responsible:	Integrated Master Psychology

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIPSI	168	Official Curricular Structure	1	-	3	30	81

Teaching language

Suitable for English-speaking students

Objectives

Enable students with basic concepts and methodologies of analysis in Human Formal, Population, Cytogenetics, Molecular Genetics and its applications in the field of psychology. It is expected that the acquired conceptual background and analytical skills will be helpful in the fields of applied psychology, teaching, research and others with more applied purposes.

Learning outcomes and competences

It is intended to provide students with the basics of the different areas of human genetics that allow the future professional to work in situations involving psychological matter pathologies transmitted genetically.

Working method

Presencial

Program

Formal Genetics

Mendelian theory of heredity.

Intra-allelic Interactions: dominance, recessivity, codominance

Multiallelism

Phenotypic expression and gene interactions

Penetrance and expressivity

Lethal genes. Epistasy. Pleiotropy.

Transmission patterns: homogametic and heterogametic systems

Extra-nuclear genomes: mitochondrial DNA

 

 Population Genetics

Concept of population. Estimating gene frequencies by direct counting.

Hardy-Weinberg Principle. Applicability conditions. Autosomal and heterosomal loci

 

Cytogenetics

Chromosome theory of heredity

Chromatin and chromosome structure

Chromosomal mutation (numeric and structural)    

 

Biochemical genetics

Inborn errors of metabolism

Metabolic chains: epi and hypostasis

Collinearity between gene and protein

 

Molecular Genetics 

Mutation at gene level

Coordination of differentiation gene expression

Molecular markers

 

Genetics in psychology

Hereditability

Mental retardation: metabolic errors and chromosomal anomalies.

Behavior genetic analysis.

Genetic counseling

Mandatory literature

GRIFFITHS AJF, MILLER JH, SUZUKI DT, LEWONTIN RC, GELBART WM; An introduction to genetic analysis, W.H. Freeman , 2007. ISBN: 0-19-530761-5
MOTTA PA ; Genética humana aplicada a psicologia e toda a área biomédica, Guanabara Koogan, 2005. ISBN: 8527709600

Complementary Bibliography

JOBLING M, HURLES M, TYLER-SMITH, C. ; JOBLING M, HURLE Human evolutionary genetics: Origins, Peoples and Disease, Garland Science.. ISBN: 9780815341857
LEWIS R ; Human genetics: concepts and applications. 9th ed, McGRAW-HILL, 2009. ISBN: 978-0-07-352527-3
MOTTA PA ; Genética em psicologia., Guanabara Koogan, 1993
PLOMIN R, DEFRIES JC, MCCLEARN GE, MCGUFFIN P; Behavioral Genetics (5th ed.), New York.Worth Publishers, 2011
REGATEIRO FJ ; Manual de genética médica, Imprensa da Universidade de Coimbra, 2003. ISBN: 972-8704-12-7

Teaching methods and learning activities

Theoretical-practical exposure and resolution / discussion of standard situations.

Evaluation Type

Evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	100,00
Total:	100,00

Amount of time allocated to each course unit

designation	Time (hours)
Estudo autónomo	53,00
Frequência das aulas	28,00
Total:	81,00

Eligibility for exams

The attendance of classes is advisable, although not obligatory due to logistical difficulties.
Once present, students should be active in class, contributing to their good functioning.

Calculation formula of final grade

In the final exam, the student must achieve a minimum score of 10 points to pass.

Classification improvement

It involves conducting further examination once, until the time of the subsequent school year the feature that in which the student has and use that UC has provided examination.