Valorisation of kitul, an overlooked food plant: Phenolic profiling of fruits and inflorescences and assessment of their effects on diabetes-related targets

• Tipo: Artigo em Revista Científica Internacional
• Data: 2021

Autores

Ferreres, F (Autor) Outra; Andrade, C (Autor) Outra; Gomes, NGM (Autor) Outra; Paula B Andrade (Autor) FFUP; Gil Izquierdo, A (Autor) Outra; David M Pereira (Autor) FFUP; Suksungworn, R (Autor) Outra; Duangsrisai, S (Autor) Outra; Videira, RA (Autor) Outra; Patricia Valentao (Autor) FFUP

Revista

Título: Food Chemistry

Vol. 342

ISSN: 0308-8146

Editora: Elsevier

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-00S-XC1

DOI: 10.1016/j.foodchem.2020.128323

Abstract (EN): Caryota urens L. has long been valued as a traditional food, the edible fruits being eaten raw and the inflorescences commonly used on sweet sap and flour production. In the current work, the phenolic profile of methanol extracts obtained from the inflorescences and fruits was unveiled for the first time, nine caffeic acid derivatives being identified and quantified. Since kitul products have been reported for their antidiabetic properties, extracts radical scavenging activity and a-amylase, a-glucosidase and aldose reductase inhibitory activity were assessed. The inflorescences' extract was particularly active against yeast a-glucosidase (IC50= 1.53 mu g/mL), acting through a non-competitive inhibitory mechanism. This activity was also observed in enzyme-enriched homogenates obtained from human Caco-2 cells (IC50 = 64.75 mu g/mL). Additionally, the extract obtained from the inflorescences showed no cytotoxicity on HepG2, AGS and Caco-2 cell lines. Our data suggest that C. urens inflorescences can support the development of new functional foods with a-glucosidase inhibitory activity.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9