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José Matos

Fotografia de José Bernardo Almeida Garrett de Noronha Matos
Nome: José Bernardo Almeida Garrett de Noronha Matos
Sigla: JBAGNM
Estado: Ativo
R-000-R02
0000-0001-6397-2104
0B14-BC34-07D0
25937449800

Funções

Carreira: Pessoal Docente de Universidades
Grupo profissional: Docente
Vínculo: Outras Colabs. -> Docente parceiro
Departamento Académico: Departamento de Biomedicina

Cargos

Cargo Data de Início
Membro da Comissão Cientifica Programa Doutoral em Neurociências 2019-04-24

Apresentação Pessoal

Holds a graduation (2007) and a MSc (2008) in Biochemistry (FCUP and ICBAS-UP, Portugal), as well as a Ph.D. (2014) in Biomedical Sciences by the University of Porto (ICBAS-UP). Worked as a young researcher at Arrhenius Institute, Stockholm University, and as a Cellular and Molecular Scientist in a Biopharmaceutical company (Phyzat Biopharmaceuticals, Lda); JBNM is an Assistant Professor of Pharmacology and Neurosciences at the Department of Imuno-Physiology and Pharmacology (ICBAS-UP), and cooperates other faculties, namely FMUP.

JBNM has over 15 years of experience in pre-clinical R&D projects in the biomedical field and has been involved in 15 different projects, both as a researcher or Principal Investigator. His research is focused on cell ageing and on new pharmacological targets in pluripotent/immunomodulatory mesenchymal stem cells (MSCs) for treating bone and cartilage disorders. JBNM holds a strong scientific background and expertise on MSC and lentiviral vector-based silencing techniques (RNAi) and has proposed new and innovative cell-rejuvenating methods using purinergic receptor modulating drugs, with significant clinical application. JBNM has post-graduation expertise in Live cell Imaging Techniques and Imaging Processing applied to life sciences for development of innovative therapeutic solutions in collaboration with national/international research teams and hospitals.

JBNM actively cooperates in projects designed to understand the biological activity profile of snake venom components in the context of neuromuscular transmission, namely bothropstoxin-I from Bothrops jararacussu and crotoxin from Crotalus durissus terrificus. He is a member of the scientific committee of the Doctoral Programme in Neuroscience since 2019. He is currently supervising PhD and master’s students, as well as postdocs. JBNM has been invited to be part of several evaluation committees (EC), to elaborate seminars and workshops in the context of RNAi and cell senescence, and to participate as a reviewer for several international peer reviewed journals. 

Most relevant international scientific papers:

My Bibliography - NCBI (nih.gov)

Recent projects:

JBNM (PI): New insights of the purinome in predicting bone healing by mesenchymal stromal cells in osteoporotic patients (2022-2023). Fundação para a Ciência e Tecnologia: Projetos de investigação de carácter exploratório (PeX), EXPL/MED-FAR/1065/2021.

JBNM (Researcher): Regeneration of the ageing human bone by purinome-activated mesenchymal stem cells – pre-clinical studies (2018-2021). Portugal2020: Projetos de Investigação Científica e Desenvolvimento Tecnológico (IC&DT): AAC nº 02/SAICT/2017 - Candidatura nº 029398. FCT, PTDC/MEDFAR/ 29398/2017, Fundo Europeu de Desenvolvimento Regional (FEDER, European Union, POCI-01-0145-FEDER-029398).

JBNM (Researcher): Purinome-rejuvenated autologous STEM cells against COVID-19. Who’s gonna win the ageing battle? (2020-2021). FCT: RESEARCH 4 COVID; – ID: 613459351; FCT nº 402.

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