Novel beta-cyclodextrin modified CdTe quantum dots as fluorescence nanosensor for acetylsalicylic acid and metabolites

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

Algarra, M (Autor) Outra; Campos, BB (Autor) Outra; Aguiar, FR (Autor) Outra; Rodriguez Borges, JE (Autor) FCUP; Esteves da Silva, JCGE (Autor) FCUP

Revista

Título: Materials Science and Engineering C

Vol. 32

Páginas: 799-803

ISSN: 0928-4931

Editora: Elsevier

Indexação

ISI Web of Knowledge - 20 Citações

Scopus - 21 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia dos materiais

Outras Informações

ID Authenticus: P-002-AMA

DOI: 10.1016/j.msec.2012.01.028

Abstract (EN): beta-Cyclodextrin was modified with 11-[(ethoxycarbonyl)thio]undecanoic acid and used as a capping agent, together with mercaptosuccinic acid, to prepare water-stable CdTe quantum dots. The water soluble quantum dot obtained displays fluorescence with a maximum emission at 425 nm (under excitation at 300 nm) with lifetimes of 0.53, 4.8, 181, and 44.1 ns, respectively. The S-beta CD-MSA-CdTe can act as a nanoprobe that is due to the affinity of the cyclodextrin moiety for selected substances such as acetylsalicylic acid (ASA) and its metabolites as foreign species. The fluorescence of the S-beta CD-MSA-CdTe is enhanced on addition of ASA. Linear calibration plots are observed with ASA in concentrations between 0 and 1 mg/l, with a limit of detection at 8.5 x 10(-9) mol/1 (1.5 ng/ml) and a precision as relative standard deviation of 1% (0.05 mg/l). The interference effect of certain compounds as ascorbic acid and its main metabolites such as salicylic, gentisic and salicyluric acid upon the obtained procedure was studied.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5