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Pharmacology I

Code: MI332     Acronym: FARM1

Classification Keyword
OFICIAL Medicine

Instance: 2021/2022 - 1S (of 13-09-2021 to 13-02-2022) Ícone do Moodle

Active? Yes
Web Page: http://moodle.up.pt
Responsible unit: Departamento de Biomedicina
Course/CS Responsible: Master Degree in Medicine

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
MIMED 290 Plano Oficial 2021 3 - 6 57 162

Teaching Staff - Responsibilities

Teacher Responsibility
Patrício Manuel Vieira Araújo Soares da Silva
Maria Augusta Vieira Coelho

Teaching language

Suitable for English-speaking students


Students are expected to learn the current knowledge on the molecular interventions of medicines and poisons and to learn the skills to evaluate new knowledge and new drugs. In detail, students are expected to know how medicines and poisons work. They are expected to know the critical actions for medical practice of drugs with multiple locals of action (drugs that act on the autonomic nervous system, drugs that act on the endocrine system, drugs that reduce the perception of pain, antibacterial drugs and antidotes). They are expected to understand the progress and constraints of current pharmacological therapy and to be able to evaluate future drug therapy.

Learning outcomes and competences

To know how medicines and poisons work. To know the critical actions for medical practice of drugs with multiple locals of action (drugs that act on the autonomic nervous system, drugs that act on the endocrine system, drugs that reduce the perception of pain, antibacterial drugs and antidotes). To understand the progress and constraints of current pharmacological therapy. To be able to evaluate future drug therapy.

Working method



The curricular unit has 6 ECTS, corresponding to the rules of the University of Porto, 56 hours of contact per student, distributed in 15 theoretical 1 hour, 14 theoretical-practical 2 hours and 7 2-hour seminars. There are 1 class for the theoretical classes and 10 for the tutorial guidelines and seminars

The curricular unit has a total workload of 6 ECTS, which corresponds to 56 contact hours per student in agreement with the bylaws of the University of Porto.
The contact hours are distributed as follows: fourteen 1-hour lectures, fourteen 2-hours theoretical-practical teaching classes and five 2-hours semminars.
There is one class for the lectures and there are 10 classes for theoretical-practical teaching and semminars 
General Pharmacology and Mechanistic Toxicology. Emphasis is given on the molecular interventions of drugs on receptors, channels, transporters and enzymes that cure, improve disease or jeopardize health and life. Quantitative aspects of Pharmacodynamics and Pharmacokinetics relevant to clinical work. Special Pharmacology of drugs that act on multiple systems: drugs that modify the sympathetic nervous system and the endocrine system; drugs that reduce perception of pain; antibacterials; antidotes. Other drugs that act on specific organs are dealt with in Pharmacology II. Methods in Clinical Pharmacology and rational drug therapy are topics for General Therapeutics and Clinical Pharmacology. Specific care for patients with acute poisoning are dealt with in Medical Toxicology.       

Mandatory literature

Brunton, L.L., Hilal-Dandan, R. & Knollmann, B.C.,; Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th edition, New York, USA: McGraw-Hill, 2018. ISBN: ISBN: 978-1-25-958474-9;
Katzung, B.G., & Trevor, A.J., ; Basic and Clinical Pharmacology, 14th edition, New York, USA: Lange, McGraw-Hill., 2018. ISBN: ISBN: 978-1-259-64115-2
Ritter, J.M., Flower, R.J., Henderson, G., Loke, Y.K. MacEawn D. & Rang, H; Rang and Dale’s Pharmacology, 9th edition., London, UK: Elsevier., 2019. ISBN: ISBN: 9780702074486;
Guimarães, S., Moura, D., & Soares-da-Silva, P.,; Terapêutica medicamentosa e suas bases farmacológicas, 6ª edição, Porto, Portugal: Porto Editora., 2014. ISBN: ISBN: 978-972-0-01794-9;

Teaching methods and learning activities

Blended learning is used (face-to-face complemented with online support). Every opportunity to approach each student personally will be considered. However due to the degrading ratio between students and paid teaching staff, adequate methods for massified learning will be used. Face-to-face learning is done by 15 weekly lectures (1 h each), 14 weekly theoretical-practical classes (2 h, each) of clinical-pharmacological cases and 7 semminars (2 h, each) with clinical vignettes. Every student is given a password to use a complete e-learning plataform on a 24-h basis. The e-learning platform is supported by moodle.up. Assessment is done with a written multiple choice test according to the American National Board of Medical Examiners, with cotation of 19 grades, and a semminar which will add 1 value to the written test.

Students are expected to acquire the knowledge, skills and competencies on medicines required by medical practice. Firstly, the syllabus contains the general properties of medicines that can be applied to every medicine. Secondly, the syllabus contains the major characteristics of systemically acting medicines which are relevant for the medical profession.


PK solutions


Health sciences > Medical sciences
Health sciences > Pharmacological sciences

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation Weight (%)
Exame 95,00
Participação presencial 5,00
Total: 100,00

Amount of time allocated to each course unit

Designation Time (hours)
Estudo autónomo 106,00
Frequência das aulas 56,00
Total: 162,00

Eligibility for exams

According to the pedagogic by-rules of FMUP.

Medical courses have recently been massified. The number of students enroled increased (currently there are 310 students in the course) whereas the number of paid teachers has decreased. Large class teaching and learning methods must be put in place. Standard medication problems are the major activities of tutorials and workshops. Multiple-choice tests are built with variations of those problems. The semminar is performed by grups of estudantes (n=11-12) naaccording pre-definidoed topics in the Pharmacology I programme da Farmacologia I. Written tests makes correction of large number of tests easy.

Calculation formula of final grade

Scores are expressed on a 0-20 scale. The final passing cut-off is 10. The final exam is a 120-min test with 100 extended-matching and multiple-choice questions designed according to the current recommendations of the American National Board of Medical Examiners. The maximal socre is 19. Active participation in 36 hours of face-to-face learning activities reported. If a student receives a total score lower than 10, the student must retest. A score of 10 or above guarantees a pass. Due to formula scoring it is required that 60% of itens are correctly answered to reach the passing cut-off. Evauation is given on cumputer. Due to the scarce number of computers, students are randomly selected to take the test in turns. Equating is carried out by the circle-arch method. If a student receives a score of 10 or more, the student can take an oral examination.

Examinations or Special Assignments

The seminar is conducted by groups of students on the basis of pre-defined topics in the Pharmacology I program.

Special assessment (TE, DA, ...)

According to the rules of the University of Porto

Classification improvement

Oral examination

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