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Endocrine Pathology I

Code: MMOM13_12     Acronym: MMOM13_12

Classification Keyword
OFICIAL Medical and Molecular Oncology

Instance: 2021/2022 - SP (of 13-09-2021 to 15-07-2022) Ícone do Moodle

Active? Yes
Responsible unit: Department of Medicine
Course/CS Responsible: Molecular Medicine and Oncology

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
MMOM 4 Plano Oficial do ano letivo 2018 1 - 3 21 81

Teaching Staff - Responsibilities

Teacher Responsibility
Davide Maurício Costa Carvalho
Paula Isabel Marques Simões de Freitas

Teaching language

Suitable for English-speaking students


Space for the acquisition, debate and deepening of Endocrinology subjects, the all-time matters and the new ones, with emphasis on molecular diagnosis and the molecular mechanisms of therapeutics.

Learning outcomes and competences

To get in depth knowledge in the fielf of: (i) endocrine disorders physiopathology understanding, with focus on the molecular mecanisms involved; (ii) molecular methods necessary to diagnosis establishments; (iii) molecular foundations of therapeutical issues.

Working method



The adrenal córtex. Congenital adrenal hiperplasia. CYP 21 gene mutations.

A clinical case of Carney Complex. PRKAR1A mutations.

Multiple endocrine neoplasia. - Insulinomas

Thyroid neoplasia  – New concepts. Familiar type of thyroid follicle epithelial carcinomas. Thyroid cancer epidemiology. Prognostic molecular markers of thyroid papillary crcinoma.

Adipose tissue. Lipodystrophies and intrathyroid lipomatosis. Genetic lypodistrophies.

Aquired lipodystrophies. Metabolic impact

Adrenal Medulla.

Familial paraganglioma. Familial types of pheocromocytoma and paragangliomas. DIPNECH

Autonomic Nervous system tumors diagnosis.

Diabetes Mellitus – Molecular markers of monogenic DM. Neonatal diabetes

MODY – Similarities and heterogeneities.

Type 1 diabetes

Pituitary tumours. Pathogenesis of pituitary tumors. Agressivity markers.

Mandatory literature

Shlomo Melmed, Ronald Koenig, Clifford Rosen, Richard Auchus, Allison Goldfine; Textbook of Endocrinology (Selected chapters)

Comments from the literature

Additional reference papers will be provided

Teaching methods and learning activities

Theoretical, tutorial orientation and seminars.

Evaluation Type

Evaluation with final exam

Assessment Components

Designation Weight (%)
Teste 100,00
Total: 100,00

Amount of time allocated to each course unit

Designation Time (hours)
Estudo autónomo 58,00
Frequência das aulas 23,00
Total: 81,00

Eligibility for exams

Presence in 80% of lectural activities.

Calculation formula of final grade

Without formula
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