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Valvular heart disease

Code: PDCCV_9     Acronym: PDCCV_9

Classification Keyword
OFICIAL Medicine

Instance: 2015/2016 - 2S Ícone do Moodle

Active? Yes
Responsible unit: Physiology and Cardiothoracic Surgery Department
Course/CS Responsible: Doctoral Programm in Cardiovascular Sciences

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
PDCCV 4 Ciências Cardiovasculares_13 1 - 4 18,5 108

Teaching Staff - Responsibilities

Teacher Responsibility
Cristina Maria Rodrigues Pinheiro Gavina

Teaching language

Suitable for English-speaking students


Approach several aspects of valvular and ischemic heart disease, from pathophysiology to treatment targets.

Learning outcomes and competences

Learning outcomes:

General aims:

1.Understand the molecular and cellular mechanisms of the valvular and ischemic heart disease.

2.Strengthen the knowledge which enables the prevention of the mentioned diseases in an early phase and their corresponding progression.

Specific aims:

1.Understand the mechanisms of the disease and interpret the clinical trials in order to improve the prevention and treatment of the valvular heart disease.

2.Understand the pathophysiology of the coronary artherosclerotic disease and the metabolic and functional consequences of myocardial ischemia.

3.Identify the indication, limitations and advantages of the available diagnosis equipment for the assessment of myocardial perfusion, function and viability.

4.Recognize the different types of acute coronary syndromes and corresponding approach.

5.Assessment of revascularization indication in chronic ischemic cardiopathy.

6.Undertake secondary prevention strategies of coronary disease.

Working method



VALVULAR HEART DISEASE: Diagnosis; Pathology; Etiology; Echocardiographic/hemodynamic evaluation; Aortic disease; Mitral valve disease; Pulmonary and tricuspid disease; Valvular prosthesis ; Valvular disease in the childhood and pregnancy; Infectious endocarditis; Basic principles of treatment; Surgical and percutaneous approach

ISCHEMIC HEART DISEASE (IHD): Pathophysiology of myocardial ischemia (MI); Coronary circulation physiology and evaluation of coronary stenosis; Atherosclerotic coronary disease (CD); Metabolic and functional consequences of MI; Myocardial perfusion, function and viability evaluation techniques used in CD: Coronariography; Echocardiography; AngioTAC; Myocardial perfusions cintigraphy; Cardiac MRI . Acute coronary syndrome I and II. Chronic MI and revascularization: Stable angina; Heart failure in IHD; Percutaneous and surgical revascularization; CD secondary prevention: chronic CD; acute coronary syndromes; Arrhythmic death prevention; Cardiac rehabilitation.

Mandatory literature

Kameswari Maganti, MD, Vera H. Rigolin, MD, Maurice Enriquez Sarano, MD, and Robert O. Bonow, MD. ; - Valvular Heart Disease: Diagnosis and Management. , Mayo Clin Proc. 85(5): 483–500, 2010
Catherine M. Otto, Robert O. Bonow. ; - Valvular Heart Disease: A Companion to Braunwald's Heart Disease, 4th Edition. , Elsevier Saunders , 2014
Douglas L. Mann, Douglas P. Zipes, Peter Libby and Robert O. Bonow, MD. ; - Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 10th Edition., Saunders, 2015
A. John Camm, Thomas F. Lüscher, and Patrick W. Serruys.; - The ESC Textbook of Cardiovascular Medicine (2 ed.)., Oxford University Press , 2009
Vlodaver, Zeev, Wilson, Robert F., Garry, Daniel. ; - Coronary Heart Disease: Clinical, Pathological, Imaging, and Molecular Profiles. , Springer, 2012

Teaching methods and learning activities

The teaching methodology will be based on theoretical classes (7 hours), theoretical-practical classes (5,5hours), lab practices (3,5 h) and seminars (2.5 hours).

Evaluation Type

Evaluation with final exam

Assessment Components

Designation Weight (%)
Exame 100,00
Total: 100,00

Eligibility for exams

The students must attend two thirds of the classes.

Calculation formula of final grade

A written final exam or an individual written project (up to 20 pages).
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