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Molecular Cytogenetics I

Code: MMOM13_6     Acronym: MMOM13_6

Keywords
Classification Keyword
OFICIAL Medical and Molecular Oncology

Instance: 2021/2022 - SP (of 13-09-2021 to 15-07-2022) Ícone do Moodle

Active? Yes
Responsible unit: Departamento de Patologia
Course/CS Responsible: Molecular Medicine and Oncology

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
MMOM 13 Plano Oficial do ano letivo 2018 1 - 3 21 81

Teaching Staff - Responsibilities

Teacher Responsibility
Manuel António Rodrigues Teixeira

Teaching - Hours

Seminar: 0,64
Others: 0,11
Type Teacher Classes Hour
Seminar Totals 1 0,642
Manuel António Rodrigues Teixeira 0,642
Others Totals 1 0,107
Manuel António Rodrigues Teixeira 0,107

Teaching language

Portuguese
Obs.: Suitable for English-speaking students

Objectives

To acquire knowledge about the various cytogenetic techniques; To know the advantages and limitations of these methodologies in various models of carcinogenesis; To understand the relevance of the genetic information for diagnosis, prognosis, treatment and follow up of neoplastic diseases; To know the somatic mutation theory of cancer, with emphasis for the relevance of fusion genes for carcinogenesis; Practical classes on FISH analysis.

Learning outcomes and competences

Acquisition of knowledge about the various cytogenetic techniques; Knowledge on the advantages and limitations of these methodologies in various models of carcinogenesis; Understading the relevance of the genetic information for diagnosis, prognosis, treatment and follow up of neoplastic diseases; Knowledge on the somatic mutation theory of cancer, with emphasis for the relevance of fusion genes for carcinogenesis.

Working method

Presencial

Program

1 - Historical perspective on the somatic mutation theory of cancer - The paradigmatic model of chronic myeloid leukemia.

2 - Relevance of cytogenetics in differential diagnosis - Examples in leukemias and sarcomas.

3 - Molecular subclassification with prognostic relevance - Examples of breast and prostate cancer.

4 - Molecular classification and targeted therapy in oncology - The lung cancer model.

5 - Practical class on FISH I.

6 - Practical class on FISH II.

7 - Clarification of doubts and exam.

Mandatory literature

Ver Moodle; Fornecida durante as aulas

Teaching methods and learning activities

Theoretical lectures in classroom. Practical classes in the lab.

Theoretical lectures venue: EPOP, IPO-Porto (3rd floor, nearby the main auditorium).
Practical lectures venue: Department of Genetics, IPO-Porto (6th floor of the Laboratory building).

Software

Moodle

keywords

Natural sciences > Biological sciences > Biology > Genetics
Health sciences > Medical sciences > Medicine > Oncology

Evaluation Type

Evaluation with final exam

Assessment Components

Designation Weight (%)
Exame 100,00
Total: 100,00

Amount of time allocated to each course unit

Designation Time (hours)
Estudo autónomo 54,00
Frequência das aulas 21,00
Total: 75,00

Eligibility for exams

Presence in 75% of the lectures.

Calculation formula of final grade

Mark on the final exame, 0-20.
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