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Methods in neuroscience

Code: PDN13_7     Acronym: PDN13_7

Keywords
Classification Keyword
OFICIAL Neurosciences

Instance: 2018/2019 - SP (of 10-09-2018 to 31-07-2019) Ícone do Moodle

Active? Yes
Responsible unit: Departamento de Biomedicina
Course/CS Responsible: PhD Neurosciences

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
PDN 6 Programa Doutoral em Neurociências 2013 1 - 6 40 162

Teaching Staff - Responsibilities

Teacher Responsibility
Fani Lourença Moreira Neto

Teaching - Hours

Theoretical and practical : 0,21
Laboratory Practice: 1,21
Type Teacher Classes Hour
Theoretical and practical Totals 6 1,26
António Avelino Ferreira Saraiva Silva 0,007
António Martins da Silva 0,023
António Albino Coelho Marques Abrantes Teixeira 0,005
Armando Cardoso 0,007
Boris Safronov 0,018
Daniela Vasconcelos Ribeiro Santos Seixas 0,01
Maria Dulce Cordeiro Madeira 0,007
Fani Lourença Moreira Neto 0,007
Filipe Almeida Monteiro 0,005
Isabel Maria Amorim Pereira Ramos 0,003
Maria Teresa Pardal Monteiro Coelho 0,01
Nikolay Vsevolodovich Lukoyanov 0,008
Pedro Alberto da Graça Pereira 0,01
Rui Manuel Cerqueira Magalhães 0,005
Sara Marta Pereira dos Santos Cavaco 0,03
Vasco Miguel Clara Lopes Galhardo 0,007
Laboratory Practice Totals 6 7,26
Ana Maria Marques Valentim 0,03
António Avelino Ferreira Saraiva Silva 0,077
António Albino Coelho Marques Abrantes Teixeira 0,077
Armando Cardoso 0,017
Boris Safronov 0,003
Carlos Manuel Gomes Reguenga 0,01
Célia da Conceição Duarte Cruz 0,023
Clara Maria Pires Costa Bastos Monteiro 0,015
Daniel Humberto Pozza 0,053
Dora Raquel da Silva Pinho 0,057
Maria Dulce Cordeiro Madeira 0,012
Fani Lourença Moreira Neto 0,082
Filipe Almeida Monteiro 0,118
Maria Isabel Torres Martins 0,078
Isaura Ferreira Tavares 0,033
Joana Maria de Pinho Ferreira Gomes 0,033
Manuela Sofia Rodrigues Morato 0,057
Miguel Filipe Tavares da Luz Soares 0,117
Nikolay Vsevolodovich Lukoyanov 0,005
Paulo Jorge da Silva Correia de Sá 0,037
Pedro Alberto da Graça Pereira 0,012
Sofia Alexandra Duque Santos Fernandes 0,037
Teresa Maria de Jesus Teixeira de Sousa 0,06
Vasco Miguel Clara Lopes Galhardo 0,057

Teaching language

Suitable for English-speaking students

Objectives

This UC aims at providing students with theoretical and practical education on various methods employed in Neuroscience, which they will have the opportunity to learn by voluntarily choosing a range of optional modules,  according to their scientific interests and putative PhD thesis.

Learning outcomes and competences

The students are offered a vast range of options distributed by eighteen distinct curricular UC components (modules),
from which they must select six. By being aware of the fundaments and mode of employment of the various techniques, the students develop the ability to correctly plan the experimental approach to various scientific questions within the neuroscience domain. These competences will help him to design a research project, either during his PhD education or after getting his(her) degree, and will allow him to understand and criticize the results of others, a skill that is crucial for the buildup of a solid body of knowledge.

Working method

Presencial

Program

Module 1 – Pharmacological Approaches-António Albino Teixeira (coordenador)

Module 2 – In vivo microdialysis- Maria Isabel Martins (coordinator)

Module 3- Microscopic Analysis-  António Avelino (coordinator)

Module 4 – Live Cell Imaging- Paulo Correia de Sá (coordinator)

Module 5 – Stereological Methods- Dulce Madeira (coordinator)

Module 6 – Neuronal Culture- Filipe Monteiro (coordinator)

Module 7 – Production and Validation of Animal Models – Fani Neto (coordinator)

Module 8- Genetically manipulated animal models- Miguel Soares (coordinator)

Module 9 – Stereotaxic Surgery and Microsurgery -Fani Neto (coordinator)

Module 10 – TractTracing Techniques- Isaura

Tavares (coordinator)

Module 11 – Electrophysiology- Vasco Galhardo (coordinator)

Module 12 – Behavioral Evaluation- Nikolay

Lukoyanova (coordinator)

Module 13 – Clinical Neurophysiology -António Martins da Silva (coordinator)

Module 14 – Brain Imaging- Isabel Ramos (coordinator)

Module 15 – Essential Bioinformatics – Filipe Monteiro (coordinator)

Module 16 - Computational Neuroscience - Mafalda Sousa (ccordinator)

Module 17 - Signal processing - Paulo Branco (coordinator)

Module 18 - Biostatistics - Rui Magalhães (coordinator)

Mandatory literature

RD Goldman & DL Specto (eds) .; Live Cell Imaging: A Laboratory Manual, , New York, NY: Cold Spring Harbour Laboratory Press, 2005
R Ian Freshney; Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, 6th Edition, New Jersey, WileyBlackwell, 2010
L. W. Haynes (editor); Neuron in Tissue Culture, IBRO Handbook series: methods in Neuroscience volume 18, New Jersey, John Wiley & Sons. ISBN: 1999
G Paxinos & C Watson (eds); The rat brain in stereotaxic coordinates, 6th Edition, Sydney, Academic press, 2006
L.R. Squire et al., (eds); Fundamental Neuroscience, 3rd Edition, Canada, Academic press, 2008

Complementary Bibliography

S Peterson; Drug microinjection in discrete brain regions.Tujunga, California, Kopf Carrier, 50 16., (www.kopfinstruments.com/Carrier/downloads/Carrier50.pdf, 1998
Schaefer PW et al.,; Diffusionweighted MR imaging of the brain. Radiology 217:33145, 2000

Teaching methods and learning activities

The student can count on the advice of his(her) tutor as to the choice of the contents that better fit them in terms
of previous training and future research. The unit is based on practical, hands on classes in laboratory environment, in small size groups, with access to all the equipment. The small size of the classes is guaranteed, if necessary, by multiplying the practical sessions. A few theoretical lessons will provide the students with the fundaments of the methodologies being addressed. The students have access to dedicated bibliography in advance and are instructed to approach professors at any time they need their support.

keywords

Health sciences > Neuroscience > Neurobiology

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Designation Weight (%)
Apresentação/discussão de um trabalho científico 20,00
Participação presencial 20,00
Teste 20,00
Trabalho escrito 20,00
Trabalho laboratorial 20,00
Total: 100,00

Amount of time allocated to each course unit

Designation Time (hours)
Apresentação/discussão de um trabalho científico 12,00
Estudo autónomo 100,00
Frequência das aulas 40,00
Trabalho escrito 10,00
Total: 162,00

Eligibility for exams

The student needs to have frequency in each of the six chosen modules with minimal approval in each; Evaluation takes into account the students' critical capacity and previous preparation for each session, as well as their performance at the lab. Depending of each module it may consist on an individual written test, written essays, oral presentation of scientific research papers, presentation and discussion of the experimental work performed in classes, design and presentation of a small exploratory project and/or student´s performance during classes.

Calculation formula of final grade

The final score is the average of the scores obtained at each of the six modules selected by the student:

(M1+M2+M3+M4+M5+M6)/6

Classification improvement

Improvement of classification will be permitted in all modules which possess a final written test to all students. In the remaining modules without a final written test, the calssification might be improved by attending again each module separatelly in a new year ("Melhoria por Frequência").
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