Biopathology I
Keywords |
Classification |
Keyword |
OFICIAL |
Medicine |
Instance: 2024/2025 - 1S 
Cycles of Study/Courses
Teaching language
Portuguese
Objectives
- Recognize “Pathology” as the study of structural, biochemical and functional changes in cells, tissues and organs, underlying the development of disease
- Understand the fundamental mechanisms of cell adaptation, injury and death
- Recognize the main types of inflammation, their mechanisms and role in tissue regeneration and repair
- Understand the mechanisms underlying changes in the vascular wall, hemostasis and thromboembolism
- Identify examples of changes in metabolism, correlating mechanisms with clinical and pathological manifestations
- Identify the main pathologies associated with the dysregulation of the immune system and its correlation with clinical immune syndromes
- Recognize the main cellular and molecular mechanisms underlying the aging process and associated pathologies
Learning outcomes and competences
- Identify and understand the main mechanisms underlying common diseases
- Recognize the main morphological characteristics of elementary lesions in Pathology
- Identify the basic pathological characteristics of common diseases
- Recognize the contribution of host and environment factors, and their interaction in the development of the disease
- Relate pathological aspects to the clinical manifestations of the disease
- Learn and use correct and appropriate medical language
- Recognize the impact of Pathology on the development of innovative diagnostic and therapeutic approaches
Working method
Presencial
Pre-requirements (prior knowledge) and co-requirements (common knowledge)
Basic knowledge of cell biology, histology, physiology and immunology
Program
- Pathology: definition, objectives, historical evolution and study methods
- Mechanisms of adaptation, injury and cell death
- Inflammation: definitions and mechanisms: acute inflammation and chronic inflammation
- Mechanisms of tissue repair and regeneration
- Arteriosclerosis, hemodynamic and thromboembolic changes
- Environment, metabolism and disease: alcoholism, tobacco consumption, diabetes mellitus and (dis) metabolic syndrome
- Immunopathology: general mechanisms, hypersensitivity reactions, autoimmunity, immunodeficiency and transplant rejection
- Cellular and molecular mechanisms involved in the aging process and associated pathologies
Mandatory literature
Vinay Kumar, Abul K. Abbas, Jon Aster (eds.).; Robbins and Cotran Pathologic Basis of Disease, 10th Edition, Elsevier, Philadelphia, 2020
David S. Strayer, Emanuel Rubin; Rubin’s Pathology: Clinicopathologic foundations of Medicine, 7th Edition, Lippincott Williams and Wilkins, Philadelphia, 2014
Vinay Kumar, Abul K. Abbas, Jon Aster (eds.).; Robbins Basic Pathology, 10th Edition, Elsevier, Philadelphia, 2017
Teaching methods and learning activities
Teaching methods
- Theoretical sessions: exposition and discussion of the main themes of the Curricular Unit, emphasizing the clinical relevance of the concepts and their present or future application. The interaction between students and teachers, through active discussion, is stimulated during these sessions.
- Theoretical-practical sessions / seminars: Consolidation of the main concepts provided in the theoretical sessions through the presentation and discussion of clinicopathological cases, scheduled for each class. The interaction between students and teachers, through active discussion, is stimulated during these sessions.
- Practical sessions: consolidation of the main concepts of the theoretical sessions through observation and discussion of key images (macroscopy, histopathology, cytopathology, etc.) representative of each theme.
Components of the evaluation
-
“Theoretical evaluation” component (TEC): Test consisting on multiple choice questions, based on the theoretical-practical sessions, classified from 0 to 20. Students are approved in the TEC if their classification equals to or exceeds 9.50 / 20.
-
“Practical evaluation” component (PEC): continuous evaluation of the practical sessions based on the presentation of clinicopathologic cases/themes, scheduled for each theoretical-pratical / seminar class. This classification is expressed from 0 to 20, and students are approved in the PEC if their classification equals to or exceeds 9.50 / 20.
Software
Moodle
keywords
Health sciences > Medical sciences > Medicine > General pathology
Evaluation Type
Distributed evaluation with final exam
Assessment Components
Designation |
Weight (%) |
Teste |
50,00 |
Trabalho escrito |
50,00 |
Total: |
100,00 |
Amount of time allocated to each course unit
Designation |
Time (hours) |
Estudo autónomo |
45,00 |
Frequência das aulas |
63,00 |
Total: |
108,00 |
Eligibility for exams
According to the General Regulation of the University of Porto Learners Assessment is considered a student fulfills the attendance to a course if, having been regularly enrolled, does not exceed the number limit faults corresponding to 25% of the foreseen classes, as regulated in the existing organizational unit.
Calculation formula of final grade
Approval in the Curricular Unit of Biopathology I implies a classification equal to or exceeding 9.50 / 20 in both components of the evaluation (TEC and PEC).
A negative result in any of the components will lead to disapproval.
The final classification of the curricular unit (FCCU) is calculated according to the formula:
FCCU = 0.5 x TEC + 0.5 x PEC
Examinations or Special Assignments
No special evaluation events or assignments are foreseen.
Internship work/project
Not applicable.
Special assessment (TE, DA, ...)
According to the Standards for Evaluation and Pedagogical Orientation of the University of Porto.
Should be performed according to the schedule approved by the Pedagogical Council
Classification improvement
Improvement of the classification in the TEC will be performed according to the schedule approved by the Pedagogical Council.
Improvement of the classification in the PEC is not foreseen according to regulations of University of Porto.
Observations
Not applicable.