Pharmacology and Therapeutics I

Code:

MIMD020208

Acronym:

FARMT I

Keywords
Classification	Keyword
OFICIAL	Clinical pharmacology

Instance: 2020/2021 - 2S

Active?	Yes
Responsible unit:	Mestrado Integrado
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	57	Official Plan from the academic year 2020/2021	2	-	4	54	108
		NÃO INSCREVER - Plano exclusivo para uso administrativo	2	-	4	54	108

Teaching language

Portuguese

Objectives

Teaching on "Pharmacology and Therapeutics I" aims at providing substantial pharmacological knowledge, in order to allow the understanding of subsequent course units related to therapeutics. It has the following objectives:

-   knowledge acquisition inGeneral pharmacology, namely, the basic pharmacological concepts, to the development of skills in the understanding and application of the principles of pharmacology, common to the use of any drug.

- knowledge acquisition in the pharmacology of drugs with actions in the main body systems, aiming a comprehensive and integrated understanding of the various pharmacological groups, for the knowledge of the actual drugs and the acquisition of skills for a critical assessment of the new drugs.

- understanding of toxics and intoxications.

Learning outcomes and competences

The course is set on a structural approach with growing complexity of its syllabus. Initially, basic concepts are introduced in the "General principles of pharmacology". Knowledge of the concepts that are common to the use of any drug, as the kinetic behavior in the body, the general mechanisms of action and the evaluation of the therapeutic effects are essential for the rational use of drugs. Next, the pharmacology of the main body systems, allowing the illustration, application and integration of the basic concepts in the understanding of the pharmacological profile of drugs or drug groups. This approachgradually instills the importance of an integrated vision of the pharmacological profile of a drug, in the optimization of the risk/benefit ratio.

Working method

Presencial

Program

- General concepts: pharmacokinetics; pharmacodynamics; variability of drug response; adverse drug reactions; pharmacological interactions. Discovery, development and evaluation of new drugs.

- Pharmacology of the body systems: peripheral nervous system; central nervous system; hemostasis and hematopoiesis; cardiovascular system; respiratory system; gastrointestinal tract; endocrine system. Immunopharmacology. Anticancer drugs. For each pharmacological group, the following aspects are considered: main drugs, mechanism of action and pharmacological actions, pharmacokinetics, therapeutic indications, adverse reactions and precautions and contraindications.

- Toxics and intoxications.

Mandatory literature

Rang HP, Ritter JM, Flower RJ, Henderson G; “Rang and Dale’s Pharmacology”, 8th edition
Dowd FJ, Johnson BS and Mariotti AJ. Mosby, 2017; “Pharmacology and Therapeutics for Dentistry”, 7ª edição
INFARMED. Ministério da Saúde; Prontuário Terapêutico

Teaching methods and learning activities

The course is organized in theoretical, theoretical-practical and practical classes. T lectures are participated classes that aim to introduce new concepts of the selected topic. TP and P classes, with a participated tutorial approach, based in a problem-based learning approach, which aims to expand and strengthen the concepts developed with T lectures. The evaluation focuses on the integration of knowledge and decision-making. It is set up on a practical component of continuous evaluation (30%) and a theoretical component (70%).

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Participação presencial	10,00
Exame	70,00
Teste	10,00
Trabalho escrito	10,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Frequência das aulas
Trabalho escrito
Total:	0,00

Eligibility for exams

According to the established by the Pedagogical Council of FMDUP.

To meet the following requirements of the continuous evaluation:

- Presentation, resolution and discussion of case-problems/clinical cases during P lectures (10% of the final classification)
- Presentation of an issue related with the syllabus, in a TP lecture (10% of the final classification) 
- Test focusing a integrative clinical case, at the end of the semester (10% of the final classification).

Calculation formula of final grade

The evaluation focuses on the integration of knowledge and decision making. The final classification  includes the components of continuous evaluation and the final examination.

A. Continuous evaluation – 30% (0 to 6, out of 20)

a. Presentation, resolution and discussion of case-problems/clinical cases during P lectures: 10%;
b. Presentation of an issue related with the syllabus, in a TP lecture: 10%;
c. Test focusing a integrative clinical case, at the end of the semester: 10%).

B. Final examination: 70% (0 to 14, out of 20) 

Final classification: A + B

Minimal classification for approval: 10

Maximal classification: 20

Classification improvement

According to that established by the Pedagogical Council of FMDUP.