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Biochemistry I

Code: MIMD010103     Acronym: BIOQ I

Keywords
Classification Keyword
OFICIAL Physical Sciences

Instance: 2020/2021 - 1S

Active? Yes
Responsible unit: Mestrado Integrado
Course/CS Responsible: Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym No. of Students Study Plan Curricular Years Credits UCN Credits ECTS Contact hours Total Time
MIMD 79 Official Plan from the academic year 2020/2021 1 - 5 81 135
NÃO INSCREVER - Plano exclusivo para uso administrativo 1 - 5 81 135
Mais informaçõesLast updated on 2020-09-28.

Fields changed: Program, Componentes de Avaliação e Ocupação, Tipo de avaliação

Teaching language

Portuguese

Objectives

1. To rationalize living systems in terms of basic Chemistry principles. To present Biological Chemistry as a mere subset of Chemistry.
2. To correlate knowledge from Organic and Inorganic Chemistry with Biological Chemistry.
3. To acquire specific knowledge about biological molecules and the cellular chemical organization.
4. Aspects of the specific Biological Chemistry of teeth and saliva.
5. To acquire some practical skills on chemical, biochemical and spectroscopic laboratorial methods.

Learning outcomes and competences

1. To rationalize living systems in terms of basic Chemistry principles. To present Biological Chemistry as a mere subset of Chemistry.

2. To correlate knowledge from Organic and Inorganic Chemistry with Biological Chemistry.

3. To acquire specific knowledge about biological molecules and the cellular chemical organization.

4. Aspects of the specific Biological Chemistry of teeth and saliva.

5. To acquire some practical skills on chemical, biochemical and spectroscopic laboratorial methods.

Working method

Presencial

Program

THEORETICAL AND THEORETICAL-PRACTICAL CLASSES

1. Elements of General Chemistry: acid/base equilibrium, pH buffers; solubility equilibrium.
2. Organic Chemistry elements.
3. Structure and function of biological molecules: carbohidrates, lipids, proteins, nucleic acids; kinetic and thermodynamic stability; intermolecular bonding and molecular recognition.
4. Enzymes: catalysis, selectivity, kinetics (Michaelis-Menten) and regulation.
5. Aspects of oral biological chemistry: saliva composition (buffer systems) and teeth compostition (minerals and solubility).
6. UV/VIS spectrophotometry; Interpretation and treatment of experimental data.

LABORATORIAL CLASSES

1. Basic chemistry laboratory techniques.
2. Preparation of a pH buffer.
3. Identification reactions for sugars.
4. Quantification of total cholesterol in human blood serum.
5. Electrophoresis of proteins in human blood serum.
6. Spectrophotometry of natural DNA.

 

Mandatory literature

P. W. Atkins and Julio de Paula; Physical Chemistry for the Life Sciences, W H Freeman & Co, 2nd Edition., 2011
T.W. Graham Solomons and Craig B. Fryhle; Organic Chemistry, John Wiley & Son, Inc, 10th Edition., 2011
K. Peter, C, Vollhardt, Neil E. Schore; Organic Chemistry Structure and Function, W. H. Freeman and Company, New York, 4th Edition., 2003
José Augusto Pereira; Apontamentos de Química Biológica, ICBAS, 2014
D.M. Vasudevan, S. Sreekumari, Kannan Vaidyanathan; Textbook of Biochemistry For Dental Students, Jaypee Brothers Medical Publishers LTD, New Delhi, Panama City, London, 2nd Edition, 2011. ISBN: 978-93-5025-488-2

Teaching methods and learning activities

Theoretical classes consist of oral and PowerPoint presentation of the different programmatic topics, with continuous interaction with the students.

Theoretical-practical classes for the elaboration of exercises related to the syllabus of the course.

Practical classes involving laboratory experiments.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation Weight (%)
Exame 100,00
Total: 100,00

Amount of time allocated to each course unit

Designation Time (hours)
Estudo autónomo 54,00
Frequência das aulas 81,00
Total: 135,00

Eligibility for exams

According to the General Regulation of the University of Porto Learners Assessment is considered a student fulfills the attendance to a course if, having been regularly enrolled, does not exceed the number limit faults corresponding to 25% of the foreseen classes, as regulated in the existing organizational unit.

Calculation formula of final grade

Classification in the distributed or final written exams.
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