Oral Biosciences I

Code:

1051

Acronym:

BIOI

Keywords
Classification	Keyword
OFICIAL	Biology

Instance: 2015/2016 - 1S

Active?	Yes
Responsible unit:	3.º Ciclo Doutoramentos
Course/CS Responsible:	Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
DMDB	0	Dental Medicine PhD - Study Plan 2009/2010	1	-	3	28	81

Teaching language

Suitable for English-speaking students

Objectives

Acquisition of knowledge related to the cellular and molecular characteristics of the oral cavity.

Development of theoretical skills on the biochemical mechanisms associated with some physiological and pathological changes of the oral cavity.

Understanding of the molecular events involved in the aging of the oral cavity.

Integration of knowledge of biology and oral biochemistry in the areas of clinical intervention of dental medicine.

Learning outcomes and competences

Studentas should have the ability to recognize, understand and interpret from a cellular and molecular point of view some physiological and pathological events that occur in the oral cavity.

Working method

Presencial

Program

Cell biology of the oral cavity: main cell types

Cellular communications in the oral cavity: cell-cell contacts, paracrinic communications and exosomes

Biochemistry of saliva

Molecular mechanisms of saliva production

Biochemical basis of some disease of the oral cavity: xerostomia, halitosis, oral cancer, dental fluorosis and dentinogenesis imperfecta

Dental aging

Salivary aging

Mandatory literature

Ferguson David B.; Oral Bioscience. ISBN: 0-7552-0229-5

Comments from the literature

Besides the book Oral Bioscience, it is suggested the reading of the following scientific papers:

Seow WK (2014) Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J. 59 Suppl 1:143-54.

Bollen CM, Beikler T (2012) Halitosis: the multidisciplinary approach. Int J Oral Sci. 4:55-63.

Denbesten P, Li W (2011) Chronic fluoride toxicity: dental fluorosis. Monogr Oral Sci. 22:81-96.

Montero PH, Patel SG (2015) Cancer of the oral cavity. Surg Oncol Clin N Am. 24:491-508.

Rajwar YC, Jain N, Bhatia G, Sikka N, Garg B, Walia E (2015) Expression and Significance of Cadherins and Its Subtypes in Development and Progression of Oral Cancers: A Review. J Clin Diagn Res. 9:ZE05-7.

Abrams AP, Thompson LA (2014) Physiology of aging of older adults: systemic and oral health considerations. Dent Clin North Am. 58:729-38.

Thomson WM, Ma S (2014) An ageing population poses dental challenges. Singapore Dent J. 35C:3-8.
Mandel L (2014) Salivary gland disorders. Med Clin North Am. 98:1407-49.

Teaching methods and learning activities

Interactive and participated lectures, with analysis of scientific papers and discussion of some clinical cases. Preparation of a written work on a topic related to the syllabus of the course.

Distributed evaluation without final exam. Students will have to make a written work, where they should apply and develop contents related to the study plan. The final work will be evaluated and the assigned rating will correspond to the final grade in the course.

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
	Trabalho escrito		100,00
	Total:	-	100,00

Calculation formula of final grade

Evaluation of the written work = final grade in the course