Molecular and Cell Biology I

Code:

MD1102

Acronym:

BCM I

Keywords
Classification	Keyword
OFICIAL	Biology

Instance: 2015/2016 - 1S

Active?	Yes
Web Page:	https://moodle.up.pt/course/view.php?id=445
Responsible unit:	Mestrado Integrado
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	79	PLANO OFICIAL 2007/2008 BOLONHA	1	-	6	90	162

Teaching language

Portuguese

Objectives

- Acquisition of theoretical and theoretical-practical skills related to the composition and the functioning of the cells
- Ability to understand the physiological characteristics of an organism as a result of different cell characteristics
- Acquisition of knowledge related to evolution and cell differentiation
- Acquisition of laboratory work skills
- Acquisition of group work skills
- Acquisition of theoretical, theoretical-practical and practical skills on the establishment, maintenance and characterization of human cell cultures

Learning outcomes and competences

At the end of this course, the student should have theoretical knowledge and demonstrate ability to prepare and execute laboratory work as well as laboratory reports and and scientific seminars.

Working method

Presencial

Program

Theoretical topics:
- General characteristics of the cell
- Cell membrane
- Transport across the membrane
- Cytoskeleton
- Nucleus and nucleolus
- Endoplasmic reticulum
- Golgi apparatus
- Mitochondria
- Lysosomes
- Peroxisomes
- Intracellular transport
- Intercellular junctions
- Extracellular matrix
- Cell adhesion
- Cell mobility
- Cell communication
- Cell death

Theoretical and practical topics:
- Cellular and molecular techniques
- Observation of different subcellular structures
- Initiation to human cell cultures

Mandatory literature

Bruce Alberts et al.; Molecular Biology of the Cell, Garland Science; 5 edition , 2008. ISBN: 0-8153-4110-5
Carlos Azevedo, Claudio Sunkel; Biologia Celular e Molecular, 5ª Edição, 2012, Lidel. ISBN: 978-972-757-692-0

Complementary Bibliography

Alberts Bruce 070; Essential Cell Biology. ISBN: 978-0-8153-4129-1
Cooper Geoffrey M.; The^cell. ISBN: 0-87893-220-7
Alberts Bruce 070; Molecular biology of the cell. ISBN: 0-8153-4072-9
Lodish Harvey; Molecular cell biology. ISBN: 0-7167-4366-3

Teaching methods and learning activities

Theoretical classes of dynamic display of the syllabus, with the involvement of students in it. Theoretical-pratical classes of demonstration of the applicability of theoretical concepts, relating them to physiological and pathological conditions, as well as its importance in the context of scientific research. Laboratory classes similar to an introductory course to cell cultures, and to scientific research, where students are placed before scientific challenges that must overcome using different experimental methodologies.

Software

Moodle

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
	Exame		80,00
	Teste		10,00
	Trabalho laboratorial		10,00
	Total:	-	100,00

Eligibility for exams

Minimum classification in the testes/exam = 7,20 (maximum = 16)
Presence in 3/4 of the classes.
Final classification > 9.5 values

Calculation formula of final grade

The Final grade is calculated using the following values: Theory (80%) + theoretical-practical evaluation (10%) + practical evaluation (10%)

Special assessment (TE, DA, ...)

These students will be alowed to have alternative exam dates, in accordance with the law.