Molecular and Cell Biology II

Code:

MD1203

Acronym:

BCM II

Keywords
Classification	Keyword
OFICIAL	Biology

Instance: 2014/2015 - 2S

Active?	Yes
Web Page:	https://moodle.up.pt/course/view.php?id=1914
Responsible unit:	Mestrado Integrado
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	93	PLANO OFICIAL 2007/2008 BOLONHA	1	-	6	90	162

Teaching language

Portuguese

Objectives

In this course we hope to provide the student with a solid knowledge about the cell molecular biology and organization, while encouraging literature research, discussion and collaboration between students in their learning process.

Learning outcomes and competences

The student must acquire theoretical knowledge in the following areas:
-Nucleic acids: general characteristics
-DNA
-RNA
-Replication
-Reparation
-Transcription and splicing
-rRNA synthesis and processing
-Translation
-iRNAs
-Cell cycle
-Meiosis
-Fertilization
-Cancer
-Oral cancer

Practical classes:
- Aquisition of technical skills related to the establishment of human cell cultures and its cellular and molecular characterization
- Aquisition of skills related to scientific investigation

Working method

Presencial

Program

-Nucleic acids: general characteristics
-DNA
-RNA
-Replication
-Reparation
-Transcription and splicing
-rRNA synthesis and processing
-Translation
-iRNAs
-Cell cycle
-Meiosis
-Fertilization
-Cancer
-Oral cancer

-Practical course about the establishment, maintenance and cellular and molecular characterization of human cell cultures

Scientific Seminar: Students (in groups of 4) prepare a seminar integrated with Biochemistry II, Epidemiology / Biostatistics II and Technologies of Information and Communication, for presentation at the end of the school year. Scientific subjects addressed in the seminars and then discussed with  professors and colleagues.

Mandatory literature

Alberts Bruce 070; Essential Cell Biology. ISBN: 978-0-8153-4129-1
Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter; Molecular Biology of the Cell, 5th edition, Garland Science, 2007. ISBN: 978-0-8153-4106-2
Cooper Geoffrey M.; The^cell. ISBN: 0-87893-220-7

Complementary Bibliography

Steven R Goodman; Medical Cell Biology, Academic Press, 2008
Lodish Harvey 070; Molecular cell biology. ISBN: 0-7167-4366-3
Alberts Bruce 070; Molecular biology of the cell. ISBN: 0-8153-4072-9
Carlos Azevedo/Claudio E. Sunkel; Biologia Celular e Molecular, 5ª Edição, Lidel, 2012

Teaching methods and learning activities

Active learning: case studies, problem-based learning and paper discussions.

Laboratory practical classes including lab experiments, writting of scientific reports and problem solving.

Software

Moodle

keywords

Natural sciences > Biological sciences > Biology > Human biology
Natural sciences > Biological sciences > Biology > Cell biology
Natural sciences > Biological sciences > Biology > Molecular biology
Natural sciences > Biological sciences > Biology > Clinical biology

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
	Participação presencial		10,00
	Prova oral		15,00
	Teste		45,00
	Trabalho laboratorial		30,00
	Total:	-	100,00

Eligibility for exams

Students must attend at least 75% of all classes to be admitted to exams. Students who fail their exams are not obliged to attend classes the following year.

It is necessary to perform the oral presentation.

Calculation formula of final grade

Theory (T) and Continuous evaluation (C) : laboratory and seminar presentation Theory: 1 test (two hours) Continuous evaluation: Laboratory work and reports, problem resolution and Integrative seminar presentation.

The final mark is calculated as follows: Theory test (T) (maximum score = 14) +  practical evaluation (maximum score = 4) + class attendance (maximum score = 2).

The student must attend at least 75% of all classes and have a final mark of at least 10/20 to pass the course.

The student must have a minimum classification (9 out of 20) in each component.

Special assessment (TE, DA, ...)

These students will be alowed to have alternative exam dates, in accordance with the law. Final mark is obtained as follows: Theory exam (maximum score  = 13) + Lab Exam (maximum score = 5).