Biochemistry I

Code:

MD1103

Acronym:

B I

Keywords
Classification	Keyword
OFICIAL	Physical Sciences

Instance: 2008/2009 - 1S

Active?	Yes
Course/CS Responsible:	Integrated Master in Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MIMD	98	PLANO OFICIAL 2007/2008 BOLONHA	1	-	6	81	162

Teaching language

Portuguese

Objectives

- Aquisition of knowledge about the fundamentals of Biochemistry and its relationship with daily life phenomenons.
- Skills of analysis, integration and discussion of aquired knowledge.
- Development of identification and interpretation skills of new situations related with aquired knowledge.
- Aquisition of laboratorial work skills.
- Understanding the relevance of Biochemistry experimental methods as a lerning basis and its aplication in Medical Sciences.

Program

THEORETICAL AND THEORETCIAL-PRACTICAL CLASSES
- Introduction to biological processes: Biochemistry and Medicine. Organic chemistry fundaments. Acids and bases.
- Structure and function of organic biomolecules: Carbohydrates. Lipids. Proteins. Nucleic acids. Enzimatic catalysis.
- 2 Themes chosen by students:
- Water. Mineral salts. Vitamins. Genetic manipulation.

PRACTICAL CLASSES
- Laboratory safety rules.
- Precision and exactness.
- Significative algarisms.
- Concentration of solutions.
- Preparation of solutions with exact concentration.
- pH determination of a solution.
- Carbohydrates identification.
- Extraction and analysis by thin layer chromatography of egg yolk lipids.
- Extraction and quantitation of egg yolk cholesterol.
- Protein identification.
- Protein quantification of a sample.
- Preparation and running of a SDS-PAGE gel.
- Protein isoelectric point determination.
- Study of salliva's composition.

Mandatory literature

Nelson David L.; Lehninger principles of biochemistry. ISBN: 0-7167-4339-6
Quintas A, Freire AP, Halpern MJ; Bioquímica – Organização Molecular da Vida, Lidel, 2008
Blackman A, Bottle S, Schmid S, Mocerino M, Wille U; Chemistry, John Wiley & Sons Ltd, 2008

Teaching methods and learning activities

Weekly classes / student

1 theoretical class of 60 minutes
1 theoretical-practical class of 90 minutes
1 practical class of 120 minutes

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Subject Classes	Participação presencial	110,50
Final report about one experience made during the semester.	Trabalho escrito
Mini-reports related with experiences made. They are made in the classes, after the practical work.	Trabalho escrito
Two worksheets about themes related with the contents of the discipline. They will be made with bibliographic consult and/or with Internet.	Trabalho escrito
Definitions of some themes related with the contents of the discipline, in order to include in WinkiDente project. The themes will be developed with Internet and bibliographic support.	Trabalho escrito
Calculation test about: significatif algararisms, concentration of solutions, pH of buffer solutions.	Exame
	Total:	-	0,00

Amount of time allocated to each course unit

Description	Type	Time (hours)	End date
The presence in the classes will be evaluated. Each missing class will correspond to a penalization in the final classification.	Frequência das aulas
	Total:	0,00

Eligibility for exams

Presence in 3/4 of the classes.
Elaboration of a complete report of an experiment made during semester.
Elaboration of one worksheet.
Elaboration of a calculation test (minimum classification = 1,23 values; maximum = 3,5 values).
Elaboration of the final exam (minimum classification= 3,5 values; maximum = 10 values)

Calculation formula of final grade

Classification in written exam (maximum = 10 values) + classification in mini-reports made in practical classes (maximum = 2,5 values) + classification in the final report (maximum = 1,5 values) + classification in the worksheets (maximum = 2 values) + classification in the WikiDente definitions (maximum = 0,5 values) + classification in the calculation test (maximum = 3,5 values) - missing classes penalties (maximum = 2 values)

Minimal classification for approval = 10,0 values