AsLn2, a luciferin-related modified tripeptide from the bioluminescent earthworm Fridericia heliota

• Type: Article in International Scientific Journal
• Date: 2014

Authors

petushkov, vn (Author) Other; dubinnyi, ma (Author) Other; rodionova, ns (Author) Other; nadezhdin, kd (Author) Other; marques, sm (Author) Other; esteves da silva, jcg (Author) FCUP; shimomura, o (Author) Other; yampolsky, iv (Author) Other

Journal

Title: Tetrahedron Letters

Vol. 55

Pages: 463-465

ISSN: 0040-4039

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 10 Citations

Scopus - 10 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-008-K0R

DOI: 10.1016/j.tetlet.2013.11.061

Abstract (EN): AsLn2, an unusual modified peptide, was isolated from the bioluminescent earthworm Fridericia heliota (Enchytraeidae). Its structure, elucidated by NMR and mass spectrometry, includes residues of tyrosine, CompX (a novel tyrosine modification product, reported in the accompanying paper), and N(omega)-acylated lysine. Chromatography, UV, and H-1 NMR data imply a close structural similarity of AsLn2 with F. heliota luciferin. AsLn2 appears to be an intermediate or by-product in F. heliota luciferin biosynthesis.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3