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GENETIC-POLYMORPHISM OF HUMAN PEPTIDASE-C, PEPC (EC3411) - FORMAL GENETIC AND POPULATION-DATA

Title
GENETIC-POLYMORPHISM OF HUMAN PEPTIDASE-C, PEPC (EC3411) - FORMAL GENETIC AND POPULATION-DATA
Type
Another Publication in an International Scientific Journal
Year
1989
Authors
KOMPF, J
(Author)
Other
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PRATA, MJ
(Author)
Other
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AMORIM, A
(Author)
FCUP
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Journal
Title: Human GeneticsImported from Authenticus Search for Journal Publications
Vol. 83
Pages: 197-198
ISSN: 0340-6717
Publisher: Springer Nature
Scientific classification
FOS: Natural sciences > Earth and related Environmental sciences
Other information
Authenticus ID: P-001-SES
Abstract (EN): Human peptidase C, PEPC (E.C.3.4.1.1), exhibits a previously undescribed genetic polymorphism, detectable in red cells or leukocytes by starch gel electrophoresis. Segregation analyses on 161 families with 469 offspring support the formal genetic hypothesis of two codominant alleles at an autosomal locus. Since four rare variants have previously been described, we named the polymorphic allele PEPC*6. Gene frequencies from southwestern Germany were PEPC*1=0.721±0.018; PEPC*6=0.276±0.018, and PEPC*R=0.003±0.002. © 1989 Springer-Verlag.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 2
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