Prognostic value of unrelated atypical serum immunofixation patterns during Multiple Myeloma therapy

• Type: Another Publication in an International Scientific Journal
• Date: 2012

Authors

guimaraes, c (Author) Other; bergantim, r (Author) Other; ramalho, r (Author) FMUP; couto, n (Author) Other; guimaraes, jt (Author) FMUP; trigo, f (Author) Other

Journal

Title: Journal of Hematology & Oncology

Vol. 5

Final page: 33

ISSN: 1756-8722

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 5 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-002-8VM

DOI: 10.1186/1756-8722-5-33

Abstract (EN): Autologous stem cell transplantation ( ASCT) is the gold standard therapy for suitable multiple myeloma ( MM) patients after induction with high dose therapy. To date, the evidence of a reliable marker of prognosis in these cases remains scarce. Our aim was to evaluate appearance of unrelated atypical serum immunofixation patterns (ASIPs) as a marker of prognosis in MM patients submitted to ASCT. We retrospectively analysed data from 65 patients. Interestingly, we observed that presence of ASIPs was associated with longer progression-free survival and longer overall survival. Our results suggested that presence of ASIPs could be a novel marker of good prognosis in MM patients submitted to ASCT.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3