AGE-RELATED QUANTITATIVE CHANGES IN INHIBITORY AXOSOMATIC SYNAPSES ON PURKINJE-CELLS OF RAT NEOCEREBELLUM (CRUS-I AND CRUS-II)

• Type: Article in International Scientific Journal
• Date: 1992

Authors

monteiro, raf (Author) Other; rocha, e (Author) ICBAS; mariniabreu, mm (Author) Other

Journal

Title: Journal of Submicroscopic Cytology and Pathology

Vol. 24

Pages: 351-357

ISSN: 1122-9497

Publisher: N I E Nuova Immagine Editrice

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 4 Citations

Scientific classification

FOS: Natural sciences > Biological sciences

Other information

Authenticus ID: P-001-PEQ

Abstract (EN): Morphometric analysis concerning inhibitory axo-somatic synapses on the somata of rat Purkinje cells was carried out. The percentage and the absolute cell surface area occupied with the synaptic junctions as well as their surface-to-somatic volume ratio exhibited significant changes with ageing (from 2 to 24 months). All the parameters revealed the smallest value at 2 months and a peak at 9 months; then, after a decline towards 12 months, they remained fairly constant until 24 months, It is suggested that the observed modifications in the synaptic parameters of the somata would have some connection with compensatory mechanisms for dendritic deafferentation seen with ageing or with the onset and development of the reproductive life of the animals.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7