QUANTITATIVE AGE-RELATED-CHANGES ON NUCLEAR INVAGINATIONS OF NEOCEREBELLAR PURKINJE-CELLS

• Type: Article in International Scientific Journal
• Date: 1992

Authors

monteiro, raf (Author) Other; rocha, e (Author) ICBAS; mariniabreu, mm (Author) Other

Journal

Title: NeuroReport

Vol. 3

Pages: 1089-1092

ISSN: 0959-4965

Publisher: Wolters Kluwer Health

Indexing

ISI Web of Knowledge - 8 Citations

Scopus - 8 Citations

Scientific classification

FOS: Medical and Health sciences > Basic medicine

Other information

Authenticus ID: P-001-NZQ

DOI: 10.1097/00001756-199212000-00014

Abstract (EN): THE aim of this study was to provide stereological data for seeking whether Purkinje neurones increase their nuclear envelope invaginations with age. The nuclear parameters considered were: ratio of absolute surface area to volume, surface density and absolute surface area. The first two parameters did not significantly change, but the absolute surface area exhibited marked variations. Regression studies showed no significant linear correlations between any of the parameters and age; so, the increase in number and/or in depth of the invaginations was not suggested. The association of invaginations with a nuclear cap of Nissl substance is a constant feature, stressing that the physiological importance of the complex is maintained throughout the ageing process.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4