Female sexual and pelvic floor muscles dysfunctions in familial amyloidotic polyneuropathy (fap -portuguese type).

• Type: Article in International Scientific Journal
• Date: 2012

Authors

gomes, mj (Author) Other; da silva, am (Author) Other; salinas, j (Author) Other; silva, mc (Author) FCUP; figueiredo, a (Author) Other; cavadas, v (Author) Other; coelho, t (Author) Other

Journal

Title: Archivos Espanoles de Urologia

Vol. 65

Pages: 476-488

ISSN: 0004-0614

Publisher: Iniestares, S.A.

Indexing

ISI Web of Knowledge - 0 Citations

Scientific classification

FOS: Medical and Health sciences > Clinical medicine

Other information

Authenticus ID: P-002-AF3

Abstract (EN): OBJECTIVES: The aim of this study was to investigate the prevalence of Sexual and Pelvic Floor Dysfunctions associated with familial type 1 Portuguese amyloid polyneuropathy (FAP). We studied women with FAP in three stages of the disease: asymptomatic women (n= 12, women in the early stage of the disease (n=8) and 3 women in the most progressive stage of the disease. We hypothesize that women with FAP suffer from pelvic floor hypotonicity, which may hinder orgasmic function and as such, lead to deteriorated sexual function. METHODS: Twenty-three women with FAP were studied. Clinical examinations were performed using the following scales: Clinical Evaluation Scale (CES), Visual Analog Scale of Quality of Life (VAS), Female Sexual Function Index (FSFI) and Pelvic Floor Manometry (PFM). RESULTS: Of the women, 5 (21.7%) had a score of < 26 on the FSFI, suggesting sexual dysfunction, 3 of which had FAP at the most progressive stage. None of the asymptomatic women had low FSFI scores. The manometrical rates (PFM) of tonus and strength of the pelvic floor showed significant differences between groups. CONCLUSION: Female sexual dysfunction (FSD) may occur in the initial stages of the disease but is more prevalent in women in the advanced stages of the disease. There is an increasing incidence of FSD as FAP disease progresses, namely in terms of HSDD and orgasmic sensation. In the asymptomatic group, the females revealed PFM alterations without stress urinary incontinence, which is regarded to be a discrete deterioration of pelvic floor muscle function.

Language: Spanish

Type (Professor's evaluation): Scientific

No. of pages: 13